Protein Alignment lab and php-3

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_499573.1
• Gene: php-3 / 176640
• WormBaseID: WBGene00004024
• Length: 275
• Species: Caenorhabditis elegans
• Alignment Length: 304
• Identity: 83/304 - (27%)
• Similarity: 119/304 - (39%)
• Gaps: 99/304 - (32%)

  Fly   301 LANNPHQQQPQVQ-QQQQQPH-QQPQHP---QNQSP-------AAHQQHH---------QNSVSP 344
            :.||.:...|.|: ....:.| :.|..|   ::.||       ||..||:         |.|||.
 Worm     8 MMNNSNMPPPFVKSSDSHETHDESPTSPFIKRSDSPATTSSAAAAAMQHNFWSTRAAQLQQSVSG 72

  Fly   345 NGGMNRQQRGGVISPGSSTSSS-----TSASNGAHPASTQSKSPNHSSSIPTYKWMQLKRNVPKP 404
            :.|         :|.|||:|:|     |.|.|.:...|..:.|| ..:.:||...|
 Worm    73 SSG---------VSSGSSSSASNNLSRTQADNHSERGSDTASSP-QVAPLPTSSGM--------- 118

  Fly   405 QAPKLPASGIASMHDYQMNGQLDMCRGGGGGGSGVGNGPVGVGGNGSPGIGGVLSVQNSL---IM 466
               .:||:..|.|:.:                 ..|..|....          :.|..|:   ..
 Worm   119 ---SMPAAAAAGMYPF-----------------NAGRFPTEFN----------MMVNQSMYNDFY 153

  Fly   467 ANSAAAAG--SAHPNGMGVGLGSGSGLSSCSLSSNTNNSG--------------RTNFTNKQLTE 515
            :||.||:.  .::|.....     :..|..||..|.|:.|              |..:|..|..|
 Worm   154 SNSLAASSWPYSYPQQYPF-----ANYSMPSLDGNLNDGGQLEWTSSSHAMRKKRKPYTKAQTLE 213

  Fly   516 LEKEFHFNRYLTRARRIEIANTLQLNETQVKIWFQNRRMKQKKR 559
            |||||.:|.|:::.:|.|:|..|.|.|.||||||||||||.||:
 Worm   214 LEKEFLYNTYVSKQKRWELAKYLHLTERQVKIWFQNRRMKDKKQ 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	29/52 (56%)
php-3	NP_499573.1	Homeodomain	200..256	CDD:459649	29/55 (53%)