Protein Alignment lab and Meox2

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_032610.1
• Gene: Meox2 / 17286
• MGIID: 103219
• Length: 303
• Species: Mus musculus
• Alignment Length: 396
• Identity: 100/396 - (25%)
• Similarity: 136/396 - (34%)
• Gaps: 154/396 - (38%)

  Fly   214 MYPTAQAQAPVHGYAGQIEEKYAAVLHASYAPGMVLEDQDPMMQQATQSQMWHHQQHLAGSYALD 278
            ::|.:|:...:||.:.          |.||          |.:..::.|.:      :|| |.
Mouse    19 LHPFSQSSLALHGRSD----------HMSY----------PELSTSSSSCI------IAG-YP-- 54

  Fly   279 AMDSLGMHAHMHH-GLPHGHLGNLANNPHQQQPQVQQQQQQPHQQPQH-PQNQSPAAHQQHHQNS 341
              :..||.|..|| |..|.|        |......||||.|..|...| ||..||.: ...|...
Mouse    55 --NEEGMFASQHHRGHHHHH--------HHHHHHHQQQQHQALQSNWHLPQMSSPPS-AARHSLC 108

  Fly   342 VSPNGGMNRQQRGGVISPGSSTSSSTSASNGAHPASTQSKSPNHSSSIPTYKWMQLKRNVPKPQA 406
            :.|:.       ||....|||            |....|.|.:..||.||
Mouse   109 LQPDS-------GGPPELGSS------------PPVLCSNSSSLGSSTPT--------------- 139

  Fly   407 PKLPASGIASMHDYQMNGQLDMCRGGGGGGSGVGNGPVGVGGNGSPGIGGVLSVQNSLIMANSAA 471
                                                    |...:||..|    :.:|..|:...
Mouse   140 ----------------------------------------GAACAPGDYG----RQALSPADVEK 160

  Fly   472 AAGSAHPNGMGVGLGSGSGLSSCSLSSNTNN---SGRTNFTNKQLTELEKEFHFNRYLTRARRIE 533
            .:||...:       ..|.....:..|..|:   ..||.||.:|:.|||.||..:.||||.||.|
Mouse   161 RSGSKRKS-------DSSDSQEGNYKSEVNSKPRKERTAFTKEQIRELEAEFAHHNYLTRLRRYE 218

  Fly   534 IANTLQLNETQVKIWFQNRRMKQKK----------------RVKEG-LIPADI-------LTQHS 574
            ||..|.|.|.|||:||||||||.|:                .||:| |:|:::       |.|..
Mouse   219 IAVNLDLTERQVKVWFQNRRMKWKRVKGGQQGAAAREKELVNVKKGTLLPSELSGIGAATLQQTG 283

  Fly   575 TSVISE 580
            .|:.:|
Mouse   284 DSLANE 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	33/52 (63%)
Meox2	NP_032610.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..191		42/221 (19%)
		Homeodomain	187..243	CDD:459649	33/55 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	278..303		4/12 (33%)