Protein Alignment lab and Hoxd11

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_032299.1
• Gene: Hoxd11 / 15431
• MGIID: 96203
• Length: 336
• Species: Mus musculus
• Alignment Length: 327
• Identity: 75/327 - (22%)
• Similarity: 104/327 - (31%)
• Gaps: 141/327 - (43%)

  Fly   357 ISPGSSTSSSTSASNGAHPASTQSKSPNHSSSIPTYKWMQLKRNVPKPQAPKLPASGIASMHDYQ 421
            ::|....|..:..|   .|:|.|...| :||::                ||.:......:..||.
Mouse    23 VAPSDFASKPSFLS---QPSSCQMTFP-YSSNL----------------APHVQPVREVAFRDYG 67

  Fly   422 MNGQLDMCRGGGGGGSGVGNGPVGVGGNGSPGIGGVLSVQNSLIMANSAAAA------------- 473
            :.......|||||||:|.|.|  |..|.|..|.||......:...|.:||||
Mouse    68 LERAKWPYRGGGGGGAGGGGG--GGPGGGGGGSGGYAPYYAAAAAAAAAAAAAEEAAMQRDLLPP 130

  Fly   474 -------------------GSAH-------------------PNGM------------------- 481
                               |..|                   |.|.
Mouse   131 AGRRPDVLFKAPEPVCGAPGPPHGPAAAASNFYSAVGRNGILPQGFDQFYEAAPGPPFAGPQPQP 195

  Fly   482 ------------------GVGLGSGS--------------------------GLSSCSLSSNT-- 500
                              |.|.|.||                          |.:....|..|
Mouse   196 APAPPQPEGAADKGDPKPGAGGGGGSPCAKATPGPEPKGAAEGGGGEGEGPPGEAGAEKSGGTVA 260

  Fly   501 ---NNSGRTNFTNKQLTELEKEFHFNRYLTRARRIEIANTLQLNETQVKIWFQNRRMKQKKRVKE 562
               :...|..:|..|:.|||:||.||.|:.:.:|::::..|.|.:.||||||||||||:||..::
Mouse   261 PQRSRKKRCPYTKYQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLNRD 325

  Fly   563 GL 564
            .|
Mouse   326 RL 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	26/52 (50%)
Hoxd11	NP_032299.1	DUF3528	26..187	CDD:432284	37/182 (20%)
		Homeodomain	265..321	CDD:459649	26/55 (47%)