Protein Alignment lab and Hoxc5

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_783857.1
• Gene: Hoxc5 / 15424
• MGIID: 96196
• Length: 222
• Species: Mus musculus
• Alignment Length: 276
• Identity: 80/276 - (28%)
• Similarity: 115/276 - (41%)
• Gaps: 70/276 - (25%)

  Fly   301 LANNPHQQQPQVQQQQQQPHQQPQHPQNQSPAAHQQHHQNSVSPNGGMNRQQRGGVISPGSSTSS 365
            :||:.::|.|.:      |....|...|...|:..|..:...   ||::........:|.:|...
Mouse     5 VANSFYKQSPNI------PAYNMQTCGNYGSASEVQASRYCY---GGLDLSITFPPPAPSNSLHG 60

  Fly   366 STSASN-GAH---PASTQSKSPNHSSSIPTYKWMQLKRNVPKPQAPKL---PASGIASMHDYQMN 423
            ...|:| .||   ||.:.:.:|.|:          |.|:...|..|.:   .|:..|.....:.:
Mouse    61 VDMAANPRAHPDRPACSAAAAPGHA----------LGRDEAAPLNPGMYSQKAARPALEERAKSS 115

  Fly   424 GQLDMCRGGGGGGSGVGNGPVGVGGNGSPGIGGVLSVQNSLIMANSAAAAGSAHPNGMGVGLGSG 488
            |::...:...|..:|:...|                            |....:|
Mouse   116 GEIKEEQAQTGQPAGLSQPP----------------------------APPQIYP---------- 142

  Fly   489 SGLSSCSLSSNTNNS-GRTNFTNKQLTELEKEFHFNRYLTRARRIEIANTLQLNETQVKIWFQNR 552
             .::...:|..|:.. .||::|..|..||||||||||||||.|||||||.|.|||.|:|||||||
Mouse   143 -WMTKLHMSHETDGKRSRTSYTRYQTLELEKEFHFNRYLTRRRRIEIANNLCLNERQIKIWFQNR 206

  Fly   553 RMKQKK----RVKEGL 564
            |||.||    :.||.|
Mouse   207 RMKWKKDSKMKSKEAL 222

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	40/52 (77%)
Hoxc5	NP_783857.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	68..141		17/110 (15%)
		Antp-type hexapeptide	140..145		1/15 (7%)
		Homeodomain	156..212	CDD:459649	40/55 (73%)