Protein Alignment lab and Hoxc4

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_038581.2
• Gene: Hoxc4 / 15423
• MGIID: 96195
• Length: 264
• Species: Mus musculus
• Alignment Length: 336
• Identity: 82/336 - (24%)
• Similarity: 110/336 - (32%)
• Gaps: 158/336 - (47%)

  Fly   292 GLPHGHLGNLANNPHQQQPQVQQQQQQPHQQPQHPQNQ---------------SPAAHQQHHQNS 341
            |..|.|               |:....|..:|.:|:.|               .||....||...
Mouse    44 GFQHHH---------------QELYPPPPPRPSYPERQYSCTSLQGPGNSRAHGPAQAGHHHPEK 93

  Fly   342 VSPNGGMNRQQRGGVISPGSSTSSSTSASNGAHPASTQSKSPNHSSSIPT-----YKWMQLKRNV 401
            ..|           :..|  :..|.||||....|.:....:|:|.||..:     |.||:
Mouse    94 SQP-----------LCEP--APLSGTSASPSPAPPACSQPAPDHPSSAASKQPIVYPWMK----- 140

  Fly   402 PKPQAPKLPASGIASMHDYQMNGQLDMCRGGGGGGSGVGNGPVGVGGNGSPGIGGVLSVQNSLIM 466
                          .:|...:|...              ||       |.|
Mouse   141 --------------KIHVSTVNPNY--------------NG-------GEP-------------- 156

  Fly   467 ANSAAAAGSAHPNGMGVGLGSGSGLSSCSLSSNTNNSGRTNFTNKQLTELEKEFHFNRYLTRARR 531
                                               ...||.:|.:|:.|||||||:||||||.||
Mouse   157 -----------------------------------KRSRTAYTRQQVLELEKEFHYNRYLTRRRR 186

  Fly   532 IEIANTLQLNETQVKIWFQNRRMKQKK-------RVKE----GLIPADILT-------QHSTSVI 578
            ||||::|.|:|.|:||||||||||.||       :|:.    |..|:.:..       .||.|.
Mouse   187 IEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPNTKVRSAPPAGAAPSTLSAATPGTSEDHSQSA- 250

  Fly   579 SEKPPQQQQPQ 589
              .||:||:.:
Mouse   251 --TPPEQQRAE 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	37/52 (71%)
Hoxc4	NP_038581.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	19..130		24/113 (21%)
		Antp-type hexapeptide	135..140		2/4 (50%)
		Homeodomain	157..213	CDD:459649	37/55 (67%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..264		10/49 (20%)