Protein Alignment lab and Hoxb9

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_032296.2
• Gene: Hoxb9 / 15417
• MGIID: 96190
• Length: 250
• Species: Mus musculus
• Alignment Length: 254
• Identity: 71/254 - (27%)
• Similarity: 97/254 - (38%)
• Gaps: 54/254 - (21%)

  Fly   338 HQNSVSPNGGMNRQQRGGVISPGSS-----TSSSTSASNGAHPASTQSKSPNHSSSIPTY----- 392
            |::..:|.......|......||.:     .|.|.........||....||:.|.|:|:.
Mouse    18 HESEDAPPAKFPSGQYANPRQPGHAEHLDFPSCSFQPKAPVFGASWAPLSPHASGSLPSVYHPYL 82

  Fly   393 --------------KWMQLKRNVPKPQAPKLPASGIASMHDYQMNGQLDMCRGGGGGGSGVGNGP 443
                          .|::     |.|:|...|..|.|::....:.|                 .|
Mouse    83 QPQGAPAAESRYLRTWLE-----PAPRAEAAPGQGQAAVKAEPLLG-----------------AP 125

  Fly   444 VGVGGNGSPGIGGVLSVQNSLIMANSAAAAGSAHPNGMGVGLGSGSGLSSCSLSSN-----TNNS 503
            ..:...|:|......|.....:::|..|..|.   |.:..|..........:.|:|     ::..
Mouse   126 GELLKQGTPEYSLETSAGREAVLSNQRAGYGD---NKICEGSEDKERPDQTNPSANWLHARSSRK 187

  Fly   504 GRTNFTNKQLTELEKEFHFNRYLTRARRIEIANTLQLNETQVKIWFQNRRMKQKKRVKE 562
            .|..:|..|..||||||.||.||||.||.|:|..|.|:|.||||||||||||.||..||
Mouse   188 KRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKMNKE 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	34/52 (65%)
Hoxb9	NP_032296.2	Hox9_act	1..172	CDD:461369	31/178 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	21..48		4/26 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	160..182		3/21 (14%)
		Homeodomain	186..242	CDD:459649	34/55 (62%)