Protein Alignment lab and Hoxb8

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_034591.1
• Gene: Hoxb8 / 15416
• MGIID: 96189
• Length: 243
• Species: Mus musculus
• Alignment Length: 284
• Identity: 76/284 - (26%)
• Similarity: 100/284 - (35%)
• Gaps: 99/284 - (34%)

  Fly   351 QQRGG----VISPGSSTSSSTSASNGAHPASTQS--KSPNHSSSIPTYKWMQLKRNVPKPQAPKL 409
            |..||    |..|.|..|..       ||:..|.  ..|:..|:.|
Mouse    30 QDLGGRPTVVYGPSSGGSFQ-------HPSQIQEFYHGPSSLSTAP------------------- 68

  Fly   410 PASGIASMHDYQMNGQLDMCRGGGGGGSGVGNGPVGVGGNGSPG-IGGVLSVQNSLIMANSAAAA 473
                      ||.|                   |..|..:|.|| ..|...:|...:.
Mouse    69 ----------YQQN-------------------PCAVACHGDPGNFYGYDPLQRQSLF------- 97

  Fly   474 GSAHPNGMGVG---LGSGSGLSSCSLSSNTNNS------------------GRTNFTNKQLTELE 517
            |:..|:.:...   |.:.|||...:..|..:.|                  ||..::..|..|||
Mouse    98 GAQDPDLVQYADCKLAAASGLGEEAEGSEQSPSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELE 162

  Fly   518 KEFHFNRYLTRARRIEIANTLQLNETQVKIWFQNRRMKQKKRVKEGLIPADILTQHSTSVISEKP 582
            |||.||.||||.||||:::.|.|.|.||||||||||||.||...:...|:....|...    ||.
Mouse   163 KEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEEL----EKE 223

  Fly   583 PQQQQPQPPELQLKSQGSDLGGNE 606
            ..::.|:..|     ||....|::
Mouse   224 KLERAPETAE-----QGDAQKGDK 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	33/52 (63%)
Hoxb8	NP_034591.1	Antp-type hexapeptide	134..139		0/4 (0%)
		Homeodomain	147..203	CDD:459649	34/55 (62%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	203..243		10/49 (20%)