Protein Alignment lab and Hoxb4

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_034589.3
• Gene: Hoxb4 / 15412
• MGIID: 96185
• Length: 250
• Species: Mus musculus
• Alignment Length: 368
• Identity: 89/368 - (24%)
• Similarity: 124/368 - (33%)
• Gaps: 136/368 - (36%)

  Fly   238 VLHASYAPGMVLEDQDPMMQQATQSQMWHHQQHLAGSYALDAMDSLGMHAHMHHGLPHGHLGNLA 302
            :::::|     ::.:.|..::.:||. :....|..|.||.......|..       |....|..|
Mouse     7 LINSNY-----VDPKFPPCEEYSQSD-YLPSDHSPGYYAGGQRRESGFQ-------PEAAFGRRA 58

  Fly   303 ----------NNPHQQQPQVQQQQQQPHQQPQHPQNQSPAAHQQHHQNSVSPNGGMNRQQRGGVI 357
                      .:|....|       .|...|..|...||.|..|....::.|..|    ||...:
Mouse    59 PCTVQRYAACRDPGPPPP-------PPPPPPPPPPGLSPRAPVQPTAGALLPEPG----QRSEAV 112

  Fly   358 SPGSSTSSSTSASNGAHPASTQSKSPNHSS--SIPTYKWMQLKRNVPKPQAPKLPASGIASMHDY 420
            |  ||......|.|..||      ||:||:  ....|.||:                   .:|
Mouse   113 S--SSPPPPPCAQNPLHP------SPSHSACKEPVVYPWMR-------------------KVH-- 148

  Fly   421 QMNGQLDMCRGGGGGGSGVGNGPVGVGGNGSPGIGGVLSVQNSLIMANSAAAAGSAHPNGMGVGL 485
                                                                ..:.:||..|
Mouse   149 ----------------------------------------------------VSTVNPNYAG--- 158

  Fly   486 GSGSGLSSCSLSSNTNNSGRTNFTNKQLTELEKEFHFNRYLTRARRIEIANTLQLNETQVKIWFQ 550
                         ......||.:|.:|:.|||||||:||||||.||:|||:.|.|:|.|:|||||
Mouse   159 -------------GEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHALCLSERQIKIWFQ 210

  Fly   551 NRRMKQKKRVKEGLIPADILTQHSTSVISEKPPQQQQPQPPEL 593
            |||||.||..|   :|...:....|:..:..||.:....||.|
Mouse   211 NRRMKWKKDHK---LPNTKIRSGGTAGAAGGPPGRPNGGPPAL 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	36/52 (69%)
Hoxb4	NP_034589.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..133		34/157 (22%)
		Antp-type hexapeptide	140..145		2/4 (50%)
		Homeodomain	162..218	CDD:459649	36/55 (65%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	219..250		7/33 (21%)