Protein Alignment lab and Hoxb3

DIOPT Version :9

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001073338.1
• Gene: Hoxb3 / 15410
• MGIID: 96184
• Length: 433
• Species: Mus musculus
• Alignment Length: 382
• Identity: 121/382 - (31%)
• Similarity: 147/382 - (38%)
• Gaps: 123/382 - (32%)

  Fly   236 AAVLHASYA--PGMVLEDQD----PMMQQATQSQMWHHQQHLAGSYALDA--MDSLGMHAHMHHG 292
            ||.|...|:  ||......|    |..|.||         ||.|.|...|  :.|||      :.
Mouse    11 AAALFGGYSSYPGSNGFGYDGPPQPPFQAAT---------HLEGDYQRSACSLQSLG------NA 60

  Fly   293 LPHGHLGNLANNPHQQQPQVQQQQQQPHQQPQHPQNQSPAAHQQHHQNSVSPNGGMNRQQRGGVI 357
            .||.....|  |....:|.:     .|...|..|.:..|:|
Mouse    61 APHAKSKEL--NGSCMRPGL-----APEPLPAPPGSPPPSA------------------------ 94

  Fly   358 SPGSSTSSSTSASNGAHPA-STQSKSPNHSSSIPT---YKWMQLKRNVPKPQAPKLPASGIASMH 418
            :|.|:||:|   :||..|: |...|....|:|..|   :.||:..|     |..||..|.
Mouse    95 APTSTTSNS---NNGGGPSKSGPPKCGAGSNSTLTKQIFPWMKESR-----QTSKLKNSS----- 146

  Fly   419 DYQMNGQLDMCRGGGGGGSGVGNGPVGVGGNGSPGIGGVLSVQNSLIMANSAAAAGSAHPNGMGV 483
                .|..:.|.||||||.|.|.     ||.||.|.||
Mouse   147 ----PGTAEGCGGGGGGGGGGGG-----GGGGSSGGGG--------------------------- 175

  Fly   484 GLGSGSGLSSCSLSSNTNNSGRTNFTNKQLTELEKEFHFNRYLTRARRIEIANTLQLNETQVKIW 548
              |.|.|.......|..:...||.:|:.||.||||||||||||.|.||:|:||.|.|:|.|:|||
Mouse   176 --GGGGGGDKSPPGSAASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIW 238

  Fly   549 FQNRRMKQKKRVK-EGLI-------PADILTQ--HST----SVISEKPPQQQQPQPP 591
            |||||||.||..| :||.       ||....|  .||    :.:....|....|.||
Mouse   239 FQNRRMKYKKDQKAKGLASSSGGPSPAGSPPQPMQSTAGFMNALHSMTPSYDSPSPP 295

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeobox	505..557	CDD:278475	37/51 (73%)
Hoxb3	NP_001073338.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..124		20/94 (21%)
		Antp-type hexapeptide	129..134		1/4 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	136..195		26/106 (25%)
		Homeobox	195..248	CDD:365835	37/52 (71%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	249..276		7/26 (27%)
		DUF4074	369..431	CDD:372548
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	389..433

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900