Protein Alignment lab and Hoxa9

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_034586.1
• Gene: Hoxa9 / 15405
• MGIID: 96180
• Length: 271
• Species: Mus musculus
• Alignment Length: 314
• Identity: 84/314 - (26%)
• Similarity: 111/314 - (35%)
• Gaps: 79/314 - (25%)

  Fly   273 GSYALDAMDSLGMHAHMHHGLPHGHLGNLANNPHQQQPQVQQQQQQP------------HQQPQH 325
            |:|.:|:. .||..|....|......|.|...|.|.....:.....|            ...|.|
Mouse     8 GNYYVDSF-LLGADAADELGAGRYAPGTLGQPPRQAAALAEHPDFSPCSFQSKAAVFGASWNPVH 71

  Fly   326 P--QNQSPAA-HQQHHQNSVSPNGGMNRQQRGGVISPGSSTSSSTSASNGAHPASTQSKSPNHSS 387
            .  .|..||| :..||...|.|...:                 :.:|.:|.:..|....:|...|
Mouse    72 AAGANAVPAAVYHHHHHPYVHPQAPV-----------------AAAAPDGRYMRSWLEPTPGALS 119

  Fly   388 --SIPTYKWMQLKRNVPKP------QAPKLPASGIASMHDYQMNG-QLDMCRGGGGGGSGVGNGP 443
              .:|:.:...:|   |:|      ..|.|....: |:.||.... .:|..:....|.....|..
Mouse   120 FAGLPSSRPYGIK---PEPLSARRGDCPTLDTHTL-SLTDYACGSPPVDREKQPSEGAFSENNAE 180

  Fly   444 VGVGGNGSPGIGGVLSVQNSLIMANSAAAAGSAHPNGMGVGLGSGSGLSSCSLSSNTNNSGRTNF 508
            ...||:..|            |..|:.||..                     |.:.:....|..:
Mouse   181 NESGGDKPP------------IDPNNPAANW---------------------LHARSTRKKRCPY 212

  Fly   509 TNKQLTELEKEFHFNRYLTRARRIEIANTLQLNETQVKIWFQNRRMKQKKRVKE 562
            |..|..||||||.||.||||.||.|:|..|.|.|.||||||||||||.||..|:
Mouse   213 TKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKKINKD 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	34/52 (65%)
Hoxa9	NP_034586.1	Hox9_act	1..192	CDD:461369	43/217 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	154..197		10/54 (19%)
		Homeodomain	206..262	CDD:459649	34/55 (62%)