Protein Alignment lab and Hoxa4

DIOPT Version :9

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_032291.1
• Gene: Hoxa4 / 15401
• MGIID: 96176
• Length: 285
• Species: Mus musculus
• Alignment Length: 310
• Identity: 93/310 - (30%)
• Similarity: 121/310 - (39%)
• Gaps: 77/310 - (24%)

  Fly   291 HGLPHGHLGNLANNPHQQQPQVQQQ--QQQPHQQPQHPQNQSPAAHQQHHQNSVSPNGGMNRQQR 353
            ||.|.|..|.:...|...:||....  ...||...|.|...:|.|.:..:...:.|
Mouse    26 HGGPGGGDGAVGGGPGYPRPQSAPHLPAPNPHAARQPPAYYAPRAREPSYPGGLYP--------- 81

  Fly   354 GGVISPGSSTSSSTSASNGAHPA-STQSKSPN-HSSSIPTYKWMQLKRNVPKPQAPKLPASGIAS 416
                   :..::...|..||.|| ..||.:|. |.|              |.||.|..|..
Mouse    82 -------APAAACPYACRGASPARPEQSPAPGAHPS--------------PAPQPPAPPRH---- 121

  Fly   417 MHDYQMNGQLDMCRGGGGGGSGVGNGPVGVGGNGSPGIGGVLSVQNSLIMANSAAAAGSAHPNGM 481
                        |..|       ...|....|..:|..        .|::|:.    |.|.|.|.
Mouse   122 ------------CAPG-------PTTPAVATGGSAPAC--------PLLLADQ----GPAGPKGK 155

  Fly   482 GVGLGSGSGLSSCSLSSNTNNSG-----RTNFTNKQLTELEKEFHFNRYLTRARRIEIANTLQLN 541
            ...:.........|..:::.|.|     ||.:|.:|:.||||||||||||||.||||||:||.|:
Mouse   156 EPVVYPWMKKIHVSAVNSSYNGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLS 220

  Fly   542 ETQVKIWFQNRRMKQKKRVKEGLIPADILTQHSTSVISEKPPQQQQPQPP 591
            |.||||||||||||.||..|   :|...:...:|:.....||.:.|...|
Mouse   221 ERQVKIWFQNRRMKWKKDHK---LPNTKMRSSNTASAPAGPPGKAQTHSP 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeobox	505..557	CDD:278475	40/51 (78%)
Hoxa4	NP_032291.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	19..70		13/43 (30%)
		Antp-type hexapeptide	159..164		0/4 (0%)
		Homeobox	183..236	CDD:278475	40/52 (77%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	238..285		7/33 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.900