Protein Alignment lab and Hoxa2

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_034581.1
• Gene: Hoxa2 / 15399
• MGIID: 96174
• Length: 372
• Species: Mus musculus
• Alignment Length: 194
• Identity: 68/194 - (35%)
• Similarity: 86/194 - (44%)
• Gaps: 46/194 - (23%)

  Fly   386 SSSIPTYKWMQLKRNVPKPQAPKLPA--SGIASMHDYQMNGQLDMCRGGGGGGSGVGNGPVG--V 446
            ||||.| ..:.....:|.|....:|:  .|....|                 |:|||..|..  .
Mouse    34 SSSIKT-STLSHSTLIPPPFEQTIPSLNPGSHPRH-----------------GAGVGGRPKSSPA 80

  Fly   447 GGNGSPGIGGVL-----------SVQNSLIMANSAAAAGSA---HPNGMGVGLGSGSGLSSCSLS 497
            |..|||...|.|           .......:..:||:.|.|   |...:.:..|||.|
Mouse    81 GSRGSPVPAGALQPPEYPWMKEKKAAKKTALPPAAASTGPACLGHKESLEIADGSGGG------- 138

  Fly   498 SNTNNSGRTNFTNKQLTELEKEFHFNRYLTRARRIEIANTLQLNETQVKIWFQNRRMKQKKRVK 561
               :...||.:||.||.|||||||||:||.|.||:|||..|.|.|.|||:||||||||.|::.:
Mouse   139 ---SRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQ 199

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	37/52 (71%)
Hoxa2	NP_034581.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	48..95		16/63 (25%)
		Antp-type hexapeptide	96..101		0/4 (0%)
		Homeodomain	140..196	CDD:459649	37/55 (67%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..225		1/6 (17%)