Protein Alignment lab and Hoxa1

DIOPT Version :9

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_034579.3
• Gene: Hoxa1 / 15394
• MGIID: 96170
• Length: 336
• Species: Mus musculus
• Alignment Length: 497
• Identity: 131/497 - (26%)
• Similarity: 173/497 - (34%)
• Gaps: 191/497 - (38%)

  Fly   122 SAAEYGITTSTTTGNPGTPLHPSSHSPADSYYESDSVHSYYATAAVATVAPPSNSSPITAANASA 186
            |..||.|..|..:|......:||.|.           .:.:.:.||:..:...:...:.......
Mouse     8 SFLEYPILGSGDSGTCSARAYPSDHG-----------ITTFQSCAVSANSCGGDDRFLVGRGVQI 61

  Fly   187 TS-------NTQQQQQQAAIISSEN-GMMYTNLDC--MYPTAQAQAPVHGYA----GQIEEKYAA 237
            :|       :.....|.|...:|.| |:.|::..|  .|......||...|.    ..:...|..
Mouse    62 SSPHHHHHHHHHHHPQTATYQTSGNLGISYSHSSCGPSYGAQNFSAPYGPYGLNQEADVSGGYPP 126

  Fly   238 VLHASYAPGMVLEDQDPMMQQATQSQMWHHQQHLAGSYALDAMDSLGMHAHMHHGLPHGHLGNLA 302
            ...|.|:..:    ..||:|.      .||.|..||.       ::|...::||.  :|
Mouse   127 CAPAVYSGNL----STPMVQH------HHHHQGYAGG-------TVGSPQYIHHS--YG------ 166

  Fly   303 NNPHQQQPQVQQQQQQPHQQPQHPQNQSP--AAHQQHHQNSVSPNGGMNRQQRGGVISPGSSTSS 365
                        |:||......:..:.||  |:||:                  ...||.|.|||
Mouse   167 ------------QEQQTLALATYNNSLSPLHASHQE------------------ACRSPASETSS 201

  Fly   366 STSASNGAHPASTQSKSPNHSSSIPTYKWMQLKRNVPKPQAPKLPASGIASMHDYQMNGQLDMCR 430
                     ||.             |:.||::|||.||
Mouse   202 ---------PAQ-------------TFDWMKVKRNPPK--------------------------- 217

  Fly   431 GGGGGGSGVGNGPVG-VGGNGSPGIGGVLSVQNSLIMANSAAAAGSAHPNGMGVGLGSGSGLSSC 494
                      .|.|| .|..|.|
Mouse   218 ----------TGKVGEYGYVGQP------------------------------------------ 230

  Fly   495 SLSSNTNNSGRTNFTNKQLTELEKEFHFNRYLTRARRIEIANTLQLNETQVKIWFQNRRMKQKKR 559
                   |:.|||||.|||||||||||||:|||||||:|||.:||||||||||||||||||||||
Mouse   231 -------NAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKR 288

  Fly   560 VKEGLIPADILTQHSTSVISEKPPQQQQPQPPELQLKSQGSD 601
            .||||:|....|...:...:|:..::..|.|......|..||
Mouse   289 EKEGLLPISPATPPGSDEKTEESSEKSSPSPSAPSPASSTSD 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeobox	505..557	CDD:278475	46/51 (90%)
Hoxa1	NP_034579.3	COG5576	177..>287	CDD:227863	75/235 (32%)
		Homeobox	234..287	CDD:365835	47/52 (90%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	104	1.000	Domainoid score	I6687
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003011
OrthoInspector	1	1.000	-	-		otm43494
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45946
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2567
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.030