Protein Alignment lab and Mnx1

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_064328.2
• Gene: Mnx1 / 15285
• MGIID: 109160
• Length: 404
• Species: Mus musculus
• Alignment Length: 380
• Identity: 104/380 - (27%)
• Similarity: 142/380 - (37%)
• Gaps: 134/380 - (35%)

  Fly   323 PQHPQNQS-PAAHQQHHQNSVSPNGGMNRQQRGGVISPGSSTSSSTSASNGAHPASTQ-SKSPNH 385
            |:....|| |.|.......:||..|      |||  |.|..|||  .||....|||:: :.:|..
Mouse    18 PRAASTQSAPLALVTSLATTVSGPG------RGG--SGGGGTSS--GASRSCSPASSEATAAPGD 72

  Fly   386 SSSIPTYKWMQLKRNVPKPQAPKLPASGIASMHDYQMNGQLDMCRGGGGGGSGVGNGP------- 443
                      :|:...|.|  |:|.|:..|.:   ...|.|     |.|||.|...||
Mouse    73 ----------RLRAESPSP--PRLLAAHCALL---PKPGFL-----GAGGGGGAAGGPGTPHHHA 117

  Fly   444 ---------------------VGVGGNGSPGIGGVLSVQNSL----IMANSAAAAGSA------- 476
                                 :|:...|:.| |..|..|.:|    :.:.|||||.:|
Mouse   118 HPGAAAAAAAAAAAAAAGGLALGLHPGGAQG-GAGLPAQAALYGHPVYSYSAAAAAAALAGQHPA 181

  Fly   477 ----HPNGMG---------VGLGSGS-----------------GLSSCSLSSNTNNSG-----RT 506
                :|...|         :.||:.:                 .:...|..:.:|..|     ||
Mouse   182 LSYSYPQVQGAHPAHPADPIKLGASTFQLDQWLRASTAGMILPKMPDFSSQAQSNLLGKCRRPRT 246

  Fly   507 NFTNKQLTELEKEFHFNRYLTRARRIEIANTLQLNETQVKIWFQNRRMKQKKRVKEGLIPADILT 571
            .||::||.|||.:|..|:||:|.:|.|:|.:|.|.||||||||||||||.|:
Mouse   247 AFTSQQLLELEHQFKLNKYLSRPKRFEVATSLMLTETQVKIWFQNRRMKWKR------------- 298

  Fly   572 QHSTSVISEKPPQQQQPQPPELQLKSQGSDLGGNELATGAPSTPTTAMTLTAPTS 626
                    .|..::|..|..|   |.:|   ||.....|.....|....:..|.|
Mouse   299 --------SKKAKEQAAQEAE---KQKG---GGGGTGKGGSEEKTEEELMGPPVS 339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	33/52 (63%)
Mnx1	NP_064328.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	36..80		18/63 (29%)
		Homeodomain	242..298	CDD:459649	33/55 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	299..404		12/47 (26%)