Protein Alignment lab and Dbx1

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001005232.1
• Gene: Dbx1 / 13172
• MGIID: 94867
• Length: 335
• Species: Mus musculus
• Alignment Length: 306
• Identity: 79/306 - (25%)
• Similarity: 117/306 - (38%)
• Gaps: 81/306 - (26%)

  Fly   375 PASTQSKSPNHSSSI----------PTYKWMQLKRNVP----KPQAPKLPASGIASMHDYQMNGQ 425
            |.|.||....|||.:          |||    |.|::|    .|.:.:.|    |::.|   :|.
Mouse    26 PQSLQSAFSGHSSFLVEDLIRISRPPTY----LSRSIPAASLSPPSQEAP----AALAD---SGT 79

  Fly   426 LDMCRGGGGGGSGVGNGP-VGVGGNGSP-----GIGGVLSVQNSLIMANSAAAAGSAHPNGMGVG 484
            .|:  |..|.||..|:.| ..:.....|     |:..:||  ::.....|.|...|..|......
Mouse    80 SDL--GSPGSGSRRGSSPQTALSPASEPTFLKFGVNAILS--SAPRRETSPALLQSPPPKTFAFP 140

  Fly   485 LGSGS--------------------GLSSCSLSSNTN-NSG---RTNFTNKQLTELEKEFHFNRY 525
            ...||                    |..|..|::... ..|   |..|::.|...|||.|...:|
Mouse   141 YFEGSFQPFIRSSYFPASSSVVPIPGTFSWPLAARGKPRRGMLRRAVFSDVQRKALEKTFQKQKY 205

  Fly   526 LTRARRIEIANTLQLNETQVKIWFQNRRMK---QKKR-------VKEGLIPADILTQHSTSVISE 580
            :::..|.::|:.|.|.::||||||||||||   .|:|       .:|..:|..:......|.:.:
Mouse   206 ISKPDRKKLASKLGLKDSQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKLNPHPDLSDVGQ 270

  Fly   581 KPPQQQQPQPPELQLKSQGSDLGGNELATGAPSTPTTAMTLTAPTS 626
            |.|..::...|            |..||..||:.|...:....|.|
Mouse   271 KGPGDEEEDNP------------GARLAYHAPADPRHLLEGPLPAS 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	24/55 (44%)
Dbx1	NP_001005232.1	PRK12323	<49..182	CDD:481241	31/147 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	58..102		13/52 (25%)
		Homeodomain	184..238	CDD:459649	24/53 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	240..335		16/77 (21%)