Protein Alignment lab and Gbx2

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_446160.1
• Gene: Gbx2 / 114500
• RGDID: 621866
• Length: 348
• Species: Rattus norvegicus
• Alignment Length: 333
• Identity: 90/333 - (27%)
• Similarity: 125/333 - (37%)
• Gaps: 89/333 - (26%)

  Fly   305 PHQQQPQVQQQQQQPHQQPQHPQNQSPAAHQQHHQNSVSPNGGMNRQQRGGVISPGSSTSSSTSA 369
            |....|.:.|...||...|.||          |||....|.|..:...:|..:     ||:..:.
  Rat    58 PPPPPPALPQAALQPALPPAHP----------HHQIPSLPTGFCSSLAQGMAL-----TSTLMAT 107

  Fly   370 SNGAHPASTQSKSPNHSSSIPTYKWMQLKRNVPKPQAPKLPASG--------IASMHD----YQM 422
            ..|..     |.||.|..:....|:      .|:|    ||..|        .|...|    ...
  Rat   108 LPGGF-----SASPQHQEAAAARKF------APQP----LPGGGNFDKSEALQADTEDGKAFLAK 157

  Fly   423 NGQL--------------DMCRGGGGGGSGVGNGPVGVGGNGSPGIGGVLSVQNSLIMANSAAAA 473
            .|.|              ...||.|...|.|.:.|.|...:        .|:::.:..::.....
  Rat   158 EGSLLAFSAAEAVQASLVGAVRGQGKDESKVEDDPKGKEES--------FSLESDVDYSSDDNLP 214

  Fly   474 G-SAH----PNGMGVGLGSGSGLSSCSLSSNTNNSGRTNFTNKQLTELEKEFHFNRYLTRARRIE 533
            | :||    |...........|.:..:.|:..|...||.||::||.|||||||..:||:...|.:
  Rat   215 GQTAHKEEDPGHALEETPQSGGAAGSTTSTGKNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQ 279

  Fly   534 IANTLQLNETQVKIWFQNRRMKQKKRVKEG---------------LIPADILTQH-STSVISEKP 582
            ||:.|:|:|.||||||||||.|. ||||.|               ::|..:   | |...|..:.
  Rat   280 IAHALKLSEVQVKIWFQNRRAKW-KRVKAGNANSKTGEPSRNPKIVVPIPV---HVSRFAIRSQH 340

  Fly   583 PQQQQPQP 590
            .|.:|.:|
  Rat   341 QQLEQARP 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	32/52 (62%)
Gbx2	NP_446160.1	Homeodomain	248..304	CDD:459649	32/56 (57%)