Protein Alignment lab and Hoxb2

DIOPT Version :9

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_598793.2
• Gene: Hoxb2 / 103889
• MGIID: 96183
• Length: 354
• Species: Mus musculus
• Alignment Length: 289
• Identity: 81/289 - (28%)
• Similarity: 106/289 - (36%)
• Gaps: 109/289 - (37%)

  Fly   360 GSST----SSSTSASNGAHPASTQSKSPNHSSSIPTYKWMQLKRNVPKP-QAPKLPASGIASMHD 419
            |:||    .|...|.:|  ||.........:...|.:.||:.|::..|| |:...|:...:|:..
Mouse    59 GASTLQRPGSQKQAGDG--PALRSPPPLPVAPPAPEFPWMKEKKSTKKPSQSAASPSPAASSVRA 121

  Fly   420 YQMNGQLDMCRGGGGGGSGVGNGPVGVGGNGSPGIGGVLSVQNSLIMANSAAAAGSAHPNGMGVG 484
            .::                           |||
Mouse   122 SEV---------------------------GSP-------------------------------- 127

  Fly   485 LGSGSGLSSCSLSSNTNNSGRTNFTNKQLTELEKEFHFNRYLTRARRIEIANTLQLNETQVKIWF 549
             ..|.||..|..|.:...  ||.:||.||.|||||||||:||.|.||:|||..|.|.|.|||:||
Mouse   128 -SDGPGLPECGGSGSRRL--RTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWF 189

  Fly   550 QNRRMKQKKRVKEGLIPADILTQHSTSVISEKPP---------QQQQPQPPELQLKSQGSDLGGN 605
            ||||||.|::           |||      .:||         |....:|.|....|.| |:..:
Mouse   190 QNRRMKHKRQ-----------TQH------REPPEGEPGGPSAQDDAGEPAEEPTVSPG-DVATH 236

  Fly   606 EL-------------ATGAPSTPTTAMTL 621
            .|             ..|||.:...|.||
Mouse   237 RLREACFHPAEAAQGPRGAPPSALPATTL 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeobox	505..557	CDD:278475	37/51 (73%)
Hoxb2	NP_598793.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	39..143		25/145 (17%)
		Antp-type hexapeptide	92..97		1/4 (25%)
		Homeobox	145..197	CDD:278475	37/51 (73%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	193..231		13/54 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	246..295		6/20 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900