Protein Alignment lab and mnx1

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_002935225.2
• Gene: mnx1 / 100496534
• XenbaseID: XB-GENE-919890
• Length: 338
• Species: Xenopus tropicalis
• Alignment Length: 302
• Identity: 82/302 - (27%)
• Similarity: 122/302 - (40%)
• Gaps: 90/302 - (29%)

  Fly   359 PGSSTS--------SSTSASNGAHPASTQSKSPNHSSSIPTYKWMQLKRNVPKPQAPK----LPA 411
            |.|.||        ||:|.||...|.|      .|:.|        |:.:.|.|  |:    :|.
 Frog    18 PKSQTSPLALVTSLSSSSLSNSGSPPS------EHTDS--------LRTDTPSP--PRTCGLVPK 66

  Fly   412 SGIASMHDYQMNGQLDMCRGGGGGGSGVGNGPVGVGGNGSPGIGGVLSVQNSLIMANSAAA-AGS 475
            .|..|.|.:.:|                   .:.:....:|||.......:.:...::||| |..
 Frog    67 PGFLSSHQHPIN-------------------MMALHPQAAPGIPPQALYGHPMYSYSAAAALAAG 112

  Fly   476 AHP-------------------NGMGVGLG----------SGSG-----LSSCSLSSNTNNSG-- 504
            .||                   :.:.:..|          |.:|     ::..:..:.:|..|
 Frog   113 QHPALSYPYPQMQGAHHAHHPVDPIKISAGTFQLDQWLRASTAGMMLPKMADFNSQAQSNLLGKC 177

  Fly   505 ---RTNFTNKQLTELEKEFHFNRYLTRARRIEIANTLQLNETQVKIWFQNRRMKQK--KRVKEGL 564
               ||.||::||.|||.:|..|:||:|.:|.|:|.:|.|.||||||||||||||.|  |:.||..
 Frog   178 RRPRTAFTSQQLLELEHQFKLNKYLSRPKRFEVATSLMLTETQVKIWFQNRRMKWKRSKKAKEQA 242

  Fly   565 I-PADILTQHSTSVISEKPPQQQQPQPPELQLKSQGSDLGGN 605
            : .|:...:.......||.|::.|.......|..:|..:.||
 Frog   243 VQDAEKQQRAGKGSCEEKCPEELQEDKNSYHLHPRGDPIKGN 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	34/54 (63%)
mnx1	XP_002935225.2	Homeodomain	178..234	CDD:459649	33/55 (60%)