Protein Alignment lab and hoxc3

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_002936696.1
• Gene: hoxc3 / 100190990
• XenbaseID: XB-GENE-5997986
• Length: 394
• Species: Xenopus tropicalis
• Alignment Length: 356
• Identity: 93/356 - (26%)
• Similarity: 122/356 - (34%)
• Gaps: 132/356 - (37%)

  Fly   296 GHLGNLANNPHQQQPQVQQQQQQPHQQPQHPQNQSPAAHQQH-------HQNSVSPNGGMNRQQR 353
            |:||       ||....:...|.|...|....|.|.:...:|       |.:.||......:...
 Frog    27 GYLG-------QQDYPSEDDYQPPFCLPPDTANGSASHKGEHSIKGIDFHLSEVSEQAQQPKSPN 84

  Fly   354 GGVISPGSSTSSSTSASNGAHPASTQSKSPN---HSSSIP--TYKWMQLKR--NVPKPQAPKLPA 411
            .....|.|:::.|.::.....|.|:...|||   ..|::|  .:.||:..|  :..|.|||.
 Frog    85 SDSPLPKSASTQSCTSKKSTGPVSSDVTSPNKKSKGSNMPKQIFPWMKETRQNSKQKKQAPP--- 146

  Fly   412 SGIASMHDYQMNGQLDMCRGGGGGGSGVGNGPVGVGGNGSPGIGGVLSVQNSLIMANSAAAAGSA 476
                                                                  .|:.|.|..|
 Frog   147 ------------------------------------------------------PADDAPAVDS- 156

  Fly   477 HPNGMGVGLGSGSGLSSCSLSSNTNNSGRTNFTNKQLTELEKEFHFNRYLTRARRIEIANTLQLN 541
                              |..|:.:...||.:||.||.||||||||||||.|.||:|:|..|.|:
 Frog   157 ------------------SFLSSASKRARTAYTNSQLVELEKEFHFNRYLCRPRRLEMAKLLNLS 203

  Fly   542 ETQVKIWFQNRRMKQKKRVK--------EGLIPADILTQHSTSVISEKPPQQQQPQPPELQLKSQ 598
            |.|:||||||||||.||..|        .||.|:                     ..|.|...|.
 Frog   204 ERQIKIWFQNRRMKFKKDHKGKGGGGSPGGLSPS---------------------SSPSLMPYSG 247

  Fly   599 GSDLGGN-----ELATGA-PSTPTTAMTLTA 623
            ...|.|:     .:|||| ..:|.....|||
 Frog   248 NLPLDGDCGYEVPMATGAYNKSPGNMYGLTA 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	37/52 (71%)
hoxc3	XP_002936696.1	Homeodomain	164..220	CDD:459649	37/55 (67%)
		DUF4074	335..392	CDD:463833