Protein Alignment lab and hoxb2

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_012808332.1
• Gene: hoxb2 / 100038155
• XenbaseID: XB-GENE-478525
• Length: 340
• Species: Xenopus tropicalis
• Alignment Length: 281
• Identity: 79/281 - (28%)
• Similarity: 105/281 - (37%)
• Gaps: 93/281 - (33%)

  Fly   357 ISPGSST----SSSTSASNGAHPASTQSKSPNHSSSIPTYKWMQLKRNVPKPQAPKLPASGIASM 417
            ::|||.:    .|...|.||.  .......|.|.::  .:.||:.|::..|
 Frog    54 LNPGSDSQIRPKSQKRAENGL--LQQPQVQPGHLAT--EFPWMKEKKSAKK-------------- 100

  Fly   418 HDYQMNGQLDMCRGGGGGGSGVGNGPVGVGGNGSPGIGGVLSVQNSLIMANSAAAAGSAHPNGMG 482
                                         ...|||         .:||....:|....|.|.|:.
 Frog   101 -----------------------------SSQGSP---------QALIPPPESAGGSPAEPPGLH 127

  Fly   483 VGLGSGSGLSSCSLSSNTNNSGRTNFTNKQLTELEKEFHFNRYLTRARRIEIANTLQLNETQVKI 547
            ...|....|             ||.:||.||.|||||||||:||.|.||:|||..|.|.|.|||:
 Frog   128 DAGGGSRRL-------------RTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKV 179

  Fly   548 WFQNRRMKQKKRVKEGLIPADILTQHSTSVISE---KPPQQQQP--QPPELQLKSQGSDLGGNEL 607
            ||||||||.|::           |||..|...|   ..|:..:|  ...:..:..||.|...:..
 Frog   180 WFQNRRMKHKRQ-----------TQHKDSQDGEHSYSNPEDGEPLDDGDDSPVYHQGLDSNDSLR 233

  Fly   608 ATGAPSTPTTAMTLTAPTSKQ 628
            .......|:|||    |:||:
 Frog   234 EQEIRKDPSTAM----PSSKE 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	37/52 (71%)
hoxb2	XP_012808332.1	Homeodomain	134..190	CDD:459649	38/68 (56%)