Protein Alignment lab and hoxd3

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_002935734.1
• Gene: hoxd3 / 100038058
• XenbaseID: XB-GENE-478462
• Length: 415
• Species: Xenopus tropicalis
• Alignment Length: 377
• Identity: 100/377 - (26%)
• Similarity: 128/377 - (33%)
• Gaps: 170/377 - (45%)

  Fly   305 PHQQQ-PQVQQQQQQPH----------QQPQHP----------------QNQSPA-AHQQHHQNS 341
            |.||| ||.......|.          :.|.|.                .||:|: ::|||...|
 Frog    44 PSQQQYPQSSLDSDYPSTACSIQPAAIRAPNHKANDISGSCMRTTSSQNSNQAPSISNQQHQAPS 108

  Fly   342 VSPNGGMNRQQRGGVISPGSSTSSSTSASNGAHPASTQSKSPNHSSSIPT------YKWMQLKRN 400
            :.|                      :|.|:|...|..:|||.|.|.|...      :.||:..|.
 Frog   109 LPP----------------------SSPSHGNSSAQKKSKSSNSSGSSQATLSKQIFPWMKESRQ 151

  Fly   401 VPKPQAPKLPASGIASMHDYQMNGQLDMCRGGGGGGSGVGNGPVGVGGNGSPGIGGVLSVQNSLI 465
            ..|                 |.|
 Frog   152 NAK-----------------QKN------------------------------------------ 157

  Fly   466 MANSAAAAGSAHPNGMGVGLGSGSGLSSCSLSSNTNNSG---RTNFTNKQLTELEKEFHFNRYLT 527
                 .::.|:.|.|           .:|...|.|..|.   ||.:|:.||.||||||||||||.
 Frog   158 -----TSSSSSTPPG-----------ENCEEKSPTGPSSKRVRTAYTSAQLVELEKEFHFNRYLC 206

  Fly   528 RARRIEIANTLQLNETQVKIWFQNRRMKQKKRVK-EGLIPADILTQHSTSVISEKPPQQQQPQPP 591
            |.||:|:||.|.|.|.|:||||||||||.||..| :|::       ||       |..|...:.|
 Frog   207 RPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKAKGIM-------HS-------PAGQSPDRSP 257

  Fly   592 ELQLKSQGSDLGG--------NELATGAPSTPTTAMT---------LTAPTS 626
            .|    .||:..|        |.|:..|||..:.|.:         .|||.|
 Frog   258 TL----SGSNHVGYSSQLPTVNSLSYDAPSPTSFAKSQQNMYGLAAYTAPLS 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	37/52 (71%)
hoxd3	XP_002935734.1	Homeodomain	181..237	CDD:459649	37/55 (67%)
		DUF4074	352..413	CDD:463833