Protein Alignment Taf1 and taf111

DIOPT Version :9

• Sequence 1: NP_001246952.1
• Gene: Taf1 / 40813
• FlyBaseID: FBgn0010355
• Length: 2172
• Species: Drosophila melanogaster
• Sequence 2: NP_593094.1
• Gene: taf111 / 2541848
• PomBaseID: SPAC2G11.14
• Length: 979
• Species: Schizosaccharomyces pombe
• Alignment Length: 1226
• Identity: 289/1226 - (23%)
• Similarity: 462/1226 - (37%)
• Gaps: 389/1226 - (31%)

  Fly   320 DQKTTNTGGSDSPSDTEEPRKRGFSLHYAAEPTPAECMSDDEDKLLGDFNSEDVRPEGPDNGENS 384
            :.:.|.:|.:|....|:..::.|..:...             :.||||.|:..:
pombe     9 ENENTKSGYNDGNDLTDLFKQNGTDMSVI-------------NSLLGDTNNPGM----------- 49

  Fly   385 DQKPKVADWRF-------GPAQIWYDMLEVPDSGEGFNYGFKTKAASTSSQPQLKDERRVKSPED 442
            ::.||:.|..|       ||....:|.:.......|.|.                      :..|
pombe    50 NESPKILDSSFENSNPQDGPNYEDFDFMGSIHKEFGNNI----------------------NEMD 92

  Fly   443 DVEDPSIADDAFLMVSQLHWEDDVV-----WDGNDIKAKVLQKLNSKTNAAGWLPSSGSRTAGAF 502
            |:||  ::||      .|..|:..|     .|..|. .|:|.|...:..|...|...|.......
pombe    93 DMED--VSDD------NLPEEEQAVNYTGDKDDEDF-GKLLAKEMGEEAAGQVLSGVGFSIPSGL 148

  Fly   503 SQPGKPSMPVGSGSSKQGSGASSKKA-----------------QQNAQAKPAE-APD-------- 541
            ..|.:||..|.|.:.:..:.|..:::                 .:..:.||.: ||.
pombe   149 VPPSEPSKTVSSTTEELQNEAQIRESIVKTFFPTFERGVLLNFSELFKPKPVKLAPPKKKTPKVC 213

  Fly   542 ---------DTWYSLF---------------PVE---------------------NEELIYYKWE 561
                     ||.|::.               |:.                     |.......||
pombe   214 VPGRLTLEVDTDYAIIFNSKKSLPLKRNVVSPISTHTKKRRRTANTSQRNDGLDLNTVFTTNDWE 278

  Fly   562 DEVIWDAQQVSKVPKPKVLTLDPN--------DENIILGIPDDIDPSKINKSTGPPPKIKIPHPH 618
            ..:|:|...|:|..:.... :|.:        ||||..|   |...||:..:...|
pombe   279 KNIIYDESDVNKTNQSSFF-IDKSLVDIDFAFDENIFDG---DTGTSKVVLNLNDP--------- 330

  Fly   619 VKKSKILLGKAGVINVLAEDTPPPPPKSPDRD--------------PFNISNDTYYTPKTEPTLR 669
                |:||             .|..||..|..              .||||||..| ...:...:
pombe   331 ----KLLL-------------QPQLPKKEDSQRSFADTHQRNSLAWKFNISNDPAY-EMLKQNHQ 377

  Fly   670 LKVGGNL----IQHSTPVVELRAPFVPTHMGPMKLRAFHRPPLKKYSHGPMAQSIPHPVFPLLKT 730
            .||...|    |:|:....:|..|:..|.:....:|::|||.:   |..|.|..:..|:....::
pombe   378 SKVRNTLSQLAIEHAAFAEKLTFPYYKTRLSKRAVRSYHRPTM---SFKPNAAIVFSPLIVRKRS 439

  Fly   731 IAKKAKQREVERIASGGGDVFFMRNPEDLSGRDGDIVLAEFCEEHPPLINQVGMCSKIKNYYKRK 795
            ..|...:||:           .....|...|.....:|.||.||||.:::..||.|:|.|||::|
pombe   440 KDKHKSEREL-----------IPTTKEITMGDTTHAILVEFSEEHPAVLSNAGMASRIVNYYRKK 493

  Fly   796 AEKDSGPQDFVYGEVAFAHT------SPF--LGILHPGQCIQAIENNMYRAPIYPHKMAHNDFLV 852
            .|:|........||   :|.      |||  .|.:.||:....:.|.|.|||::.|::...||::
pombe   494 NEQDESRPKLEVGE---SHVLDVQDRSPFWNFGSVEPGEITPTLYNKMIRAPLFKHEVPPTDFIL 555

  Fly   853 IRTRNN----YWIRSVNSIYTVGQECPLYEVPGPNSKRANNFTRDFLQVFIYRLFWKSRDNPRRI 913
            ||..::    |:::::|.::..||..|:.:||||:|::....:::.|::.::||..:|.:....|
pombe   556 IRNSSSYGSKYYLKNINHMFVSGQTFPVTDVPGPHSRKVTTASKNRLKMLVFRLIRRSPNGGLFI 620

  Fly   914 RMDDIKQAFPAHSESSIRKRLKQCADFKRTGMDSNWWVIKPEFRLPSEEEIRAMVSPEQCCAYFS 978
            |  .:.:.|...:|..||:|||:..::|:.|....:|.:|....:|.|...|:|||||..|...|
pombe   621 R--QLSKHFSDQNEMQIRQRLKEFMEYKKKGDGPGYWKLKSNEVVPDEAGTRSMVSPETVCLLES 683

  Fly   979 MIAAEQRLKDAGYGEKFLFAPQEDDDEEAQLKLDDEVKVAPWNTTRAYIQAMRGKCLLQLSGPAD 1043
            |....::|:||||| |.:....:|:|||...    |..:|||.|||.:|.|.:||.:|.|.|..|
pombe   684 MQVGVRQLEDAGYG-KTMDEINDDEDEEQPA----EQLLAPWITTRNFINATQGKAMLTLFGEGD 743

  Fly  1044 PTGCGEGFSYVRVPNKPTQTKEEQESQPKRSVTGTDADLRRLPLQRAKELLRQFKVPEEEIKKLS 1108
            |||.|||:|::|       |..:...:|    .|..||.:                ||.:.|
pombe   744 PTGIGEGYSFIR-------TSMKGGFKP----AGETADDK----------------PEPQTK--- 778

  Fly  1109 RWEVIDVVRTLSTEKAKAGEEGMDKFSRGNRFSIAEHQERYKEECQRIFDLQNRVLASSEVLSTD 1173
                                       ..:.:::|:.|..|:||..||::.|.|.|:.
pombe   779 ---------------------------NAHAYNVAKQQRAYEEEINRIWNAQKRGLSI------- 809

  Fly  1174 EAESSASEESDLEELGKNL-------ENMLSNKKTSTQLSREREELERQELLRQLDEEHGGPSGS 1231
                     ::||||.|..       :.:.||::|:      |||
pombe   810 ---------NNLEELAKKYGINSIHDDYVESNEETT------REE-------------------- 839

  Fly  1232 GGAKGAKGKDDPGQQMLATNNQGRILRITRTFRGNDGKEYTRVETVRRQPVIDAYIKIRTTKDEQ 1296
                              |.:..::|||.|.:|..:|....:.||:....||.||:|.|...|||
pombe   840 ------------------TPSSDKVLRIVRLYRDKNGNLERKQETIHDPIVIHAYLKKRREIDEQ 886

  Fly  1297 FIKQFATLDEQQKEEMKREKRRIQEQLRRIKRNQERERLAQLAQNQKLQPGGMPTSLGDPKSSGG 1361
            .....|.:....:...:|.:||::::|.:.::|.||.|                         ..
pombe   887 STALDAVVPTGDEAIDRRNRRRLEQELAKSQKNWERRR-------------------------AR 926

  Fly  1362 HSHKERDSGYKEVSPSRKKFKLKPDLKLKCGACGQVGHMRTNKACPLYSGMQSSLS 1417
            |:.||   |.......|     ||..: ||..|||||||:|||.|||:...:..|:
pombe   927 HAAKE---GINLNGEGR-----KPTTR-KCSNCGQVGHMKTNKICPLFGRPEGGLA 973

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Taf1	NP_001246952.1	TBP-binding	15..76	CDD:286347
		DUF3591	652..1114	CDD:288969	144/477 (30%)
		zf-CCHC_6	1388..>1418	CDD:291934	16/30 (53%)
		Bromo_TFIID	1518..1629	CDD:99943
		Bromo_TFIID	1640..1751	CDD:99943
taf111	NP_593094.1	TAF1	1..970	CDD:227506	288/1221 (24%)
		DUF3591	361..807	CDD:288969	153/527 (29%)
		zf-CCHC_6	946..>964	CDD:291934	13/17 (76%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	216	1.000	Domainoid score	I578
eggNOG	1	0.900	-	-		E1_COG5179
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004441
OrthoInspector	1	1.000	-	-		oto100435
orthoMCL	1	0.900	-	-		OOG6_102499
Panther	1	1.100	-	-	LDO	PTHR13900
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2307
SonicParanoid	1	1.000	-	-		X3145
TreeFam	0	0.000	Not matched by this tool.
	9	8.840