Protein Alignment Ass and ASS1

DIOPT Version :9

• Sequence 1: NP_001262324.1
• Gene: Ass / 40812
• FlyBaseID: FBgn0026565
• Length: 419
• Species: Drosophila melanogaster
• Sequence 2: XP_011517007.1
• Gene: ASS1 / 445
• HGNCID: 758
• Length: 450
• Species: Homo sapiens
• Alignment Length: 405
• Identity: 222/405 - (54%)
• Similarity: 294/405 - (72%)
• Gaps: 4/405 - (0%)

  Fly     3 KETVILAYSGGLDTSCVLKWLLDKQYEVICVLADVGQKEDFTAAEKKALKIGAKKVIVADVKQSF 67
            |.:|:|||||||||||:|.||.::.|:||..||::||||||..|.|||||:|||||.:.||.:.|
Human    42 KGSVVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQKEDFEEARKKALKLGAKKVFIEDVSREF 106

  Fly    68 VEDYIWPAVQMGLVYEERYLLGTSLARPCISVALMEVAREYGAKYLAHGATGKGNDQVRFELCAY 132
            ||::||||:|...:||:|||||||||||||:...:|:|:..||||::|||||||||||||||..|
Human   107 VEEFIWPAIQSSALYEDRYLLGTSLARPCIARKQVEIAQREGAKYVSHGATGKGNDQVRFELSCY 171

  Fly   133 ALKPDLKIIAPWRDVEFCCQFQGRQDLIAYAQQHGIEVSAKPATPWSTDANILHISYESGILEDP 197
            :|.|.:|:|||||..||..:|:||.||:.||:||||.:...|..|||.|.|::|||||:||||:|
Human   172 SLAPQIKVIAPWRMPEFYNRFKGRNDLMEYAKQHGIPIPVTPKNPWSMDENLMHISYEAGILENP 236

  Fly   198 NTVAPENLYEMTVDPLTRAPRDPVHLVIQFDRGLPSSVEDLPGGRVYTKPLEMLDFLNKLGGSYG 262
            ...||..||..|.|| .:||..|..|.|:|.:|:|..|.::..|..:...||:..:||::.|.:|
Human   237 KNQAPPGLYTKTQDP-AKAPNTPDILEIEFKKGVPVKVTNVKDGTTHQTSLELFMYLNEVAGKHG 300

  Fly   263 IGRIDIVENRFVGLKSRGVYETPGGTILFAAHQDLEVFALDREVLRTKQVLRDRMADYVYNGFWF 327
            :||||||||||:|:||||:||||.||||:.||.|:|.|.:||||.:.||.|..:.|:.||.|||.
Human   301 VGRIDIVENRFIGMKSRGIYETPAGTILYHAHLDIEAFTMDREVRKIKQGLGLKFAELVYTGFWH 365

  Fly   328 SPEAIYARKCIELAEQRVSGKVTVELAPGYCRAIARKAAKDVGALYNEQLVSMDVHGGYVPQDAG 392
            |||..:.|.||..:::||.|||.|.:..|....:.|::..   :||||:||||:|.|.|.|.||.
Human   366 SPECEFVRHCIAKSQERVEGKVQVSVLKGQVYILGRESPL---SLYNEELVSMNVQGDYEPTDAT 427

  Fly   393 GFIAINAVRIREHVR 407
            |||.||::|::|:.|
Human   428 GFININSLRLKEYHR 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ass	NP_001262324.1	Argininosuccinate_Synthase	6..401	CDD:238957	218/394 (55%)
ASS1	XP_011517007.1	Arginosuc_synth	46..439	CDD:279148	218/396 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144580
Domainoid	1	1.000	456	1.000	Domainoid score	I501
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6899
Inparanoid	1	1.050	459	1.000	Inparanoid score	I1575
Isobase	1	0.950	-	0	Normalized mean entropy	S758
OMA	1	1.010	-	-		QHG60671
OrthoDB	1	1.010	-	-		D1459745at2759
OrthoFinder	1	1.000	-	-		FOG0003927
OrthoInspector	1	1.000	-	-		oto90625
orthoMCL	1	0.900	-	-		OOG6_101359
Panther	1	1.100	-	-	LDO	PTHR11587
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2704
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	14	13.860