DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ass and Ass1

DIOPT Version :9

Sequence 1:	NP_001262324.1	Gene:	Ass / 40812	FlyBaseID:	FBgn0026565	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	NP_031520.1	Gene:	Ass1 / 11898	MGIID:	88090	Length:	412	Species:	Mus musculus

Alignment Length:	405	Identity:	224/405 - (55%)
Similarity:	296/405 - (73%)	Gaps:	4/405 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KETVILAYSGGLDTSCVLKWLLDKQYEVICVLADVGQKEDFTAAEKKALKIGAKKVIVADVKQSF 67
            |.:|:|||||||||||:|.||.::.|:||..||::||||||..|.|||||:|||||.:.||.:.|
Mouse     4 KGSVVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQKEDFEEARKKALKLGAKKVFIEDVSKEF 68

  Fly    68 VEDYIWPAVQMGLVYEERYLLGTSLARPCISVALMEVAREYGAKYLAHGATGKGNDQVRFELCAY 132
            ||::||||||...:||:|||||||||||||:...:|:|:..||||::|||||||||||||||..|
Mouse    69 VEEFIWPAVQSSALYEDRYLLGTSLARPCIARRQVEIAQREGAKYVSHGATGKGNDQVRFELTCY 133

  Fly   133 ALKPDLKIIAPWRDVEFCCQFQGRQDLIAYAQQHGIEVSAKPATPWSTDANILHISYESGILEDP 197
            :|.|.:|:|||||..||..:|:||.||:.||:||||.:...|.:|||.|.|::|||||:||||:|
Mouse   134 SLAPQIKVIAPWRMPEFYNRFKGRNDLMEYAKQHGIPIPVTPKSPWSMDENLMHISYEAGILENP 198

  Fly   198 NTVAPENLYEMTVDPLTRAPRDPVHLVIQFDRGLPSSVEDLPGGRVYTKPLEMLDFLNKLGGSYG 262
            ...||..||..|.|| .:||..|..|.|:|.:|:|..|.::..|...|..||:..:||::.|.:|
Mouse   199 KNQAPPGLYTKTQDP-AKAPNSPDVLEIEFKKGVPVKVTNIKDGTTRTTSLELFMYLNEVAGKHG 262

  Fly   263 IGRIDIVENRFVGLKSRGVYETPGGTILFAAHQDLEVFALDREVLRTKQVLRDRMADYVYNGFWF 327
            :||||||||||:|:||||:||||.||||:.||.|:|.|.:||||.:.||.|..:.|:.||.|||.
Mouse   263 VGRIDIVENRFIGMKSRGIYETPAGTILYHAHLDIEAFTMDREVRKIKQGLGLKFAELVYTGFWH 327

  Fly   328 SPEAIYARKCIELAEQRVSGKVTVELAPGYCRAIARKAAKDVGALYNEQLVSMDVHGGYVPQDAG 392
            |||..:.|.||:.:::||.|||.|.:..|....:.|::..   :||||:||||:|.|.|.|.||.
Mouse   328 SPECEFVRHCIQKSQERVEGKVQVSVFKGQVYILGRESPL---SLYNEELVSMNVQGDYEPIDAT 389

  Fly   393 GFIAINAVRIREHVR 407
            |||.||::|::|:.|
Mouse   390 GFININSLRLKEYHR 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ass	NP_001262324.1	Argininosuccinate_Synthase	6..401	CDD:238957	220/394 (56%)
Ass1	NP_031520.1	Arginosuc_synth	8..401	CDD:279148	220/396 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834696
Domainoid	1	1.000	458	1.000	Domainoid score	I491
eggNOG	1	0.900	-	-		E1_COG0137
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6899
Inparanoid	1	1.050	463	1.000	Inparanoid score	I1537
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60671
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003927
OrthoInspector	1	1.000	-	-		oto94214
orthoMCL	1	0.900	-	-		OOG6_101359
Panther	1	1.100	-	-	LDO	PTHR11587
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R97
SonicParanoid	1	1.000	-	-		X2704
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790