DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sowi and Chp1

DIOPT Version :9

Sequence 1:	NP_649671.2	Gene:	sowi / 40809	FlyBaseID:	FBgn0037460	Length:	217	Species:	Drosophila melanogaster
Sequence 2:	NP_077053.1	Gene:	Chp1 / 64152	RGDID:	620447	Length:	195	Species:	Rattus norvegicus

Alignment Length:	198	Identity:	40/198 - (20%)
Similarity:	74/198 - (37%)	Gaps:	45/198 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 IKELTLTSELSQTDITCLLVVYYKFSKANGPQCKQMTKKQFYQIFLVLFNVASVQVIE------- 81
            ::|:...:..|.:.||.|   |.:|:..:..:...::::.|.:|..:..|....::|.
  Rat    14 LEEIKKETGFSHSQITRL---YSRFTSLDKGENGTLSREDFQRIPELAINPLGDRIINAFFSEGE 75

  Fly    82 ---------RTLLAI--------TKDTKYVSPRAWIHLFDLYTTNDIQVRMRFAFEVYDTKGTGV 129
                     |||...        :||.....|           .|....::.|||.:||......
  Rat    76 DQVNFRGFMRTLAHFRPIEDNEKSKDVNGPEP-----------LNSRSNKLHFAFRLYDLDKDDK 129

  Fly   130 IDREQVGTACEKFFYGEDEDELNELKADMTEFLMKKFDLDKDGVISYEDYSTVVE----QQPILV 190
            |.|:::.............||.....||.|   :::.|.|.|..||:.::..|:|    :|.:.:
  Rat   130 ISRDELLQVLRMMVGVNISDEQLGSIADRT---IQEADQDGDSAISFTEFVKVLEKVDVEQKMSI 191

  Fly   191 EFL 193
            .||
  Rat   192 RFL 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sowi	NP_649671.2	EF-hand_7	115..179	CDD:290234	17/63 (27%)
sowi	NP_649671.2	EFh	116..178	CDD:238008	17/61 (28%)
Chp1	NP_077053.1	FRQ1	1..182	CDD:227455	36/184 (20%)
		Necessary for association with microtubule and interaction with GAPDH	2..6
		Nuclear export signal 1	138..147		0/8 (0%)
		Nuclear export signal 2	176..185		2/8 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0034
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900