DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sowi and PPP3R1

DIOPT Version :9

Sequence 1:	NP_649671.2	Gene:	sowi / 40809	FlyBaseID:	FBgn0037460	Length:	217	Species:	Drosophila melanogaster
Sequence 2:	NP_000936.1	Gene:	PPP3R1 / 5534	HGNCID:	9317	Length:	170	Species:	Homo sapiens

Alignment Length:	78	Identity:	24/78 - (30%)
Similarity:	36/78 - (46%)	Gaps:	11/78 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 DIQVRMRFAFEVYDTKGTGVIDREQVGTACEKFFYGEDEDELNELKADMTEFLMKK----FDLDK 170
            |.:.::||||.:||....|.|...::.... |...|      |.||....:.::.|    .|.|.
Human    87 DKEQKLRFAFRIYDMDKDGYISNGELFQVL-KMMVG------NNLKDTQLQQIVDKTIINADKDG 144

  Fly   171 DGVISYEDYSTVV 183
            ||.||:|::..||
Human   145 DGRISFEEFCAVV 157

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sowi	NP_649671.2	EF-hand_7	115..179	CDD:290234	21/67 (31%)
sowi	NP_649671.2	EFh	116..178	CDD:238008	20/65 (31%)
PPP3R1	NP_000936.1	FRQ1	13..157	CDD:227455	22/76 (29%)
PPP3R1	NP_000936.1	Calcineurin A binding. /evidence=ECO:0000269\|PubMed:12218175, ECO:0000269\|PubMed:12357034, ECO:0000269\|PubMed:17498738, ECO:0000269\|PubMed:22343722, ECO:0000269\|PubMed:23468591, ECO:0000269\|PubMed:26794871, ECO:0000269\|PubMed:27974827, ECO:0000269\|PubMed:8524402	131..136		0/4 (0%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0034
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810