DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sowi and CIB4

DIOPT Version :9

Sequence 1:	NP_649671.2	Gene:	sowi / 40809	FlyBaseID:	FBgn0037460	Length:	217	Species:	Drosophila melanogaster
Sequence 2:	XP_011530816.1	Gene:	CIB4 / 130106	HGNCID:	33703	Length:	201	Species:	Homo sapiens

Alignment Length:	189	Identity:	36/189 - (19%)
Similarity:	76/189 - (40%)	Gaps:	46/189 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 ALYGSLIKELTLTSELSQTDITCLLVVYYKFSKANGPQCKQMTKKQFYQIFLVLFNVASVQVIER 82
            :|...|::.||.   |::.:|.|:...:.|.....         |.:.:..|.:..|:|:..:.
Human    27 SLLCDLLQALTF---LTRNEILCIHDTFLKLCPPG---------KYYKEATLTMDQVSSLPALR- 78

  Fly    83 TLLAITKDTKYVSP------RAWIHLFDLYTTNDI-------------QVRMRFAFEVYDTKGTG 128
                       |:|      |.:.|. .:::..|:             .:::.:||.:||....|
Human    79 -----------VNPFRDRICRVFSHK-GMFSFEDVLGMASVFSEQACPSLKIEYAFRIYDFNENG 131

  Fly   129 VIDREQVGTACEKFFYGEDEDELNELKADMTEFLMKKFDLDKDGVISYEDYSTVVEQQP 187
            .||.|.:.....:....:|..|  :|..|:|..::.:.|||.|.::|:.::...:.:.|
Human   132 FIDEEDLQRIILRLLNSDDMSE--DLLMDLTNHVLSESDLDNDNMLSFSEFEHAMAKSP 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sowi	NP_649671.2	EF-hand_7	115..179	CDD:290234	18/63 (29%)
sowi	NP_649671.2	EFh	116..178	CDD:238008	18/61 (30%)
CIB4	XP_011530816.1	EFh	117..185	CDD:238008	18/69 (26%)
CIB4	XP_011530816.1	EF-hand_7	118..184	CDD:290234	18/67 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0034
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810