DRSC/TRiP Functional Genomics Resources

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Protein Alignment sowi and CHP1

DIOPT Version :10

Sequence 1:NP_649671.2 Gene:sowi / 40809 FlyBaseID:FBgn0037460 Length:217 Species:Drosophila melanogaster
Sequence 2:NP_009167.1 Gene:CHP1 / 11261 HGNCID:17433 Length:195 Species:Homo sapiens


Alignment Length:198 Identity:40/198 - (20%)
Similarity:74/198 - (37%) Gaps:45/198 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    24 IKELTLTSELSQTDITCLLVVYYKFSKANGPQCKQMTKKQFYQIFLVLFNVASVQVIE------- 81
            ::|:...:..|.:.||.|   |.:|:..:..:...::::.|.:|..:..|....::|.       
Human    14 LEEIKKETGFSHSQITRL---YSRFTSLDKGENGTLSREDFQRIPELAINPLGDRIINAFFPEGE 75

  Fly    82 ---------RTLLAI--------TKDTKYVSPRAWIHLFDLYTTNDIQVRMRFAFEVYDTKGTGV 129
                     |||...        :||.....|           .|....::.|||.:||......
Human    76 DQVNFRGFMRTLAHFRPIEDNEKSKDVNGPEP-----------LNSRSNKLHFAFRLYDLDKDEK 129

  Fly   130 IDREQVGTACEKFFYGEDEDELNELKADMTEFLMKKFDLDKDGVISYEDYSTVVE----QQPILV 190
            |.|:::.............||.....||.|   :::.|.|.|..||:.::..|:|    :|.:.:
Human   130 ISRDELLQVLRMMVGVNISDEQLGSIADRT---IQEADQDGDSAISFTEFVKVLEKVDVEQKMSI 191

  Fly   191 EFL 193
            .||
Human   192 RFL 194

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sowiNP_649671.2 EF-hand_7 114..179 CDD:463900 17/64 (27%)
CHP1NP_009167.1 Necessary for association with microtubule and interaction with GAPDH. /evidence=ECO:0000250 2..6
FRQ1 27..182 CDD:444056 34/171 (20%)
Nuclear export signal 1. /evidence=ECO:0000250 138..147 0/8 (0%)
Necessary for nuclear export signal 143..185 12/44 (27%)
Nuclear export signal 2. /evidence=ECO:0000250 176..185 2/8 (25%)
Blue background indicates that the domain is not in the aligned region.

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