DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31482 and CLEC18B

DIOPT Version :9

Sequence 1:	NP_731097.1	Gene:	CG31482 / 40806	FlyBaseID:	FBgn0051482	Length:	195	Species:	Drosophila melanogaster
Sequence 2:	NP_001011880.2	Gene:	CLEC18B / 497190	HGNCID:	33849	Length:	455	Species:	Homo sapiens

Alignment Length:	196	Identity:	47/196 - (23%)
Similarity:	72/196 - (36%)	Gaps:	46/196 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LIVLALCLLVLVIADLQEDHLNE-------------------HNRLREKHGSPP------LTLDD 46
            |:.:.|.||....|::....|.|                   ||||| ....||      |...|
Human    13 LLAVLLALLGTTWAEVWPPQLQEQAPMAGALNRKESFLLLSLHNRLR-SWVQPPAADMRRLDWSD 76

  Fly    47 ELTKGCEEYAKV-------LANNEKLEHSSSAGQNYGENLCMRSQTPLQCVQDWYDEIADYDFEK 104
            .|.:..:..|.:       ||:.  |..:...|.|. :.|.....:.::.|..|:.|...|....
Human    77 SLAQLAQARAALCGIPTPSLASG--LWRTLQVGWNM-QLLPAGLASFVEVVSLWFAEGQRYSHAA 138

  Fly   105 PQFAMST--GHFTALVWKNAKKMGIGQAKDKKGYYWV---VARYYPPVN--VNGQFEENVLPPIK 162
            .:.|.:.  .|:|.|||..:.::|.|:.....|...:   |..|.|..|  |||   :.::|..|
Human   139 GECARNATCTHYTQLVWATSSQLGCGRHLCSAGQTAIEAFVCAYSPGGNWEVNG---KTIIPYKK 200

  Fly   163 G 163
            |
Human   201 G 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31482	NP_731097.1	SCP_GAPR-1_like	21..149	CDD:240182	36/166 (22%)
CLEC18B	NP_001011880.2	SCP_euk	50..183	CDD:240180	31/136 (23%)
CLEC18B	NP_001011880.2	CLECT	310..443	CDD:153057
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820