DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG2336 and ALDH8A1

DIOPT Version :9

Sequence 1:NP_731094.3 Gene:CG2336 / 40804 FlyBaseID:FBgn0037455 Length:322 Species:Drosophila melanogaster
Sequence 2:NP_072090.1 Gene:ALDH8A1 / 64577 HGNCID:15471 Length:487 Species:Homo sapiens


Alignment Length:278 Identity:56/278 - (20%)
Similarity:100/278 - (35%) Gaps:59/278 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    35 IYNLVCNKPRDVSVPLILEIETEFKSKDSAPEKPKKVPRLSY-HSRSSSMSEDEPEPEVQVKYQW 98
            :.|:|......|...|:...|....|...:....:::.:||. |.:..|:......|        
Human   203 VVNIVFGTGPRVGEALVSHPEVPLISFTGSQPTAERITQLSAPHCKKLSLELGGKNP-------- 259

  Fly    99 NSPRLMILCEDGDINCALHYLVESLHDPFA-----CNAVATLFLQESILEEFVDRIRDRLEPLST 158
                 .|:.||.:::..:...|.|   .||     |...:.:|:|:||..||:.|..:.......
Human   260 -----AIIFEDANLDECIPATVRS---SFANQGEICLCTSRIFVQKSIYSEFLKRFVEATRKWKV 316

  Fly   159 DISGHP-VYIMTLERIGHLQAKRIVGNPKTVPENAS-----------------------PMLVYD 199
            .|...| |.|..|....||:..|.... :.:.|.|.                       |.::.|
Human   317 GIPSDPLVSIGALISKAHLEKVRSYVK-RALAEGAQIWCGEGVDKLSLPARNQAGYFMLPTVITD 380

  Fly   200 LSHRYLA-----DGPTGVITLHTFRTMKEAVELQAKEPLNFTSVCIWNEKLAAAYELVARL-SPL 258
            :......     .||  |..:..|.:.:|.:| :|.......:..:|:..:...:.:..:| |.|
Human   381 IKDESCCMTEEIFGP--VTCVVPFDSEEEVIE-RANNVKYGLAATVWSSNVGRVHRVAKKLQSGL 442

  Fly   259 IFTINCYYVNLNEITLPF 276
            ::| ||:.:  .|:.|||
Human   443 VWT-NCWLI--RELNLPF 457

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2336NP_731094.3 DUF1487 97..311 CDD:254173 45/215 (21%)
ALDH8A1NP_072090.1 ALDH_F8_HMSADH 27..485 CDD:143412 56/278 (20%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG1012
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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