DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2336 and Aldh1l1

DIOPT Version :9

Sequence 1:	NP_731094.3	Gene:	CG2336 / 40804	FlyBaseID:	FBgn0037455	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_071992.2	Gene:	Aldh1l1 / 64392	RGDID:	621294	Length:	902	Species:	Rattus norvegicus

Alignment Length:	270	Identity:	60/270 - (22%)
Similarity:	100/270 - (37%)	Gaps:	69/270 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 NRPTAISLEEEVQYI-----YKYPLL-----PTPLIDYGFIYNLVCNKPRDVSVPLILEIETEFK 59
            ||...::.:|.|...     :.|||:     ....:..|   |.|..||..|: ||......|..
  Rat   553 NRNLTLTKKEPVGVCGIVIPWNYPLMMLSWKTAACLAAG---NTVVIKPAQVT-PLTALKFAELT 613

  Fly    60 SKDSAPEKPKKV---------PRLSYH------------------SRSSSMSEDEPEPEVQVKYQ 97
            .|...|:....:         .|||.|                  .:|.::|..:   :|.::..
  Rat   614 LKAGIPKGVVNILPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKSCALSNVK---KVSLELG 675

  Fly    98 WNSPRLMILCEDGDINCALHYLVESL--HDPFACNAVATLFLQESILEEFVDRIRDRLE------ 154
            ..||  :|:..|.|:|.|:...:.|:  :....|.|...||::|||..:||.::.:.:|
  Rat   676 GKSP--LIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEESIHNQFVQKVVEEVEKMKIGN 738

  Fly   155 PLSTDIS----GHPVYIMTLERI---GHLQAKRIVGNPKTVPENA---SPMLVYDL-SHRYLAD- 207
            ||..|.:    .|..::..|...   |..:...:|.....||...   .|.:..|: .|.|:|.
  Rat   739 PLERDTNHGPQNHEAHLRKLVEYCQRGVKEGATLVCGGNQVPRPGFFFQPTVFTDVEDHMYIAKE 803

  Fly   208 ---GPTGVIT 214
               ||..:|:
  Rat   804 ESFGPIMIIS 813

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2336	NP_731094.3	DUF1487	97..311	CDD:254173	35/141 (25%)
Aldh1l1	NP_071992.2	GART	1..203
		Substrate binding. /evidence=ECO:0000250	88..90
		Aldehyde dehydrogenase	417..902		60/270 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900