DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2336 and Aldh16a1

DIOPT Version :9

Sequence 1:	NP_731094.3	Gene:	CG2336 / 40804	FlyBaseID:	FBgn0037455	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_001028878.1	Gene:	Aldh16a1 / 361571	RGDID:	1566295	Length:	802	Species:	Rattus norvegicus

Alignment Length:	315	Identity:	65/315 - (20%)
Similarity:	122/315 - (38%)	Gaps:	66/315 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 PLLPTPLI---------DYGFIYNLVCNKPRDVSVPLILEIETEFKSKDSAPEKPKKVPRLSYHS 78
            |..||||:         .:..|.|:||. |..:...|..:...:..:...|.|:.:.: |.:...
  Rat   202 PSFPTPLLLAQLAGELGSFPGILNVVCG-PVSLGPVLASQPGVQKVAFCGAVEEGRAL-RQTLAG 264

  Fly    79 RSSSMSEDEPEPEVQVKYQWNSPRLMILCEDGDINCALHYLVESLHDPFACNAVATLFLQESILE 143
            |.:::.           ....:..|::|.:..|::.|:..:|:::....:...: .|.:|||:.:
  Rat   265 RGATLG-----------LALGTESLLLLTDSADVDSAVEGVVDAVWSDRSLGGL-RLLIQESVWD 317

  Fly   144 EFVDRIRDRLEPL--------STDISGHPVYIMTLERIGHLQAKRIVGNPKT----------VPE 190
            |.:.|::.|:..:        :.|:.........|       |:..|...::          :|.
  Rat   318 EAMKRLQARMAQIRSGKGLDGAVDMGARGAAARDL-------AQSFVDEAQSQGGQVFQAGDMPS 375

  Fly   191 NA---SPMLVYDL---SHRYLADGPTGVITLHTFRTMKEAVELQAKEPLNFTSVCIWNEKLAAAY 249
            |:   ||.||..|   :....|:.|..|:....|||:|||:.|....|.. .|..:|:|:|..|.
  Rat   376 NSPFFSPTLVSGLPPAAPCAQAEVPWPVVMASPFRTVKEALALANGTPRG-GSASVWSERLGQAL 439

  Fly   250 ELVARLSPLIFTINCYYVNLNEITLPFVCNFNSAKIIDGYH------YESLTFKG 298
            ||...|.     :...::|.:.:..|.|......:....:|      ||.|...|
  Rat   440 ELGYGLQ-----VGTVWINAHGLRDPAVPTGGCKESGSSWHGGPDGLYEYLQLLG 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2336	NP_731094.3	DUF1487	97..311	CDD:254173	50/232 (22%)
Aldh16a1	NP_001028878.1	ALDH-SF	19..491	CDD:416387	65/315 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	513..554
		ALDH-SF	550..>765	CDD:416387
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810