DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2336 and Aldh1l2

DIOPT Version :9

Sequence 1:	NP_731094.3	Gene:	CG2336 / 40804	FlyBaseID:	FBgn0037455	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_001178707.2	Gene:	Aldh1l2 / 299699	RGDID:	1309458	Length:	923	Species:	Rattus norvegicus

Alignment Length:	171	Identity:	42/171 - (24%)
Similarity:	64/171 - (37%)	Gaps:	28/171 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 CNAVATLFLQESILEEFVDRIRDRL------EPL--STD--ISGHPVYIMTLERIGHLQAK---- 179
            |.|...||::|:|.:|||.|:.:.:      :||  |||  ...|..::..|.:......|
  Rat   728 CIAAGRLFVEEAIHDEFVTRVVEEIKKMKIGDPLDRSTDHGPQNHKAHLEKLLQYCETGVKEGAT 792

  Fly   180 -----RIVGNPKTVPENASPMLVYDLSHRYLAD----GPTGVITLHTFRTMKEAVELQAKEPLNF 235
                 |.|..|....|......|.|  |.|||.    ||..||:......:...::.........
  Rat   793 LVYGGRQVQRPGFFMEPTVFTGVED--HMYLAKEESFGPIMVISKFQNGDIDGVLQRANNTEYGL 855

  Fly   236 TSVCIWNEKLAAAYELVARLSPLIFTINCYYVNLNEITLPF 276
            .| .::...::.|..:..||......||.|  |..::..||
  Rat   856 AS-GVFTRDISKAMYVSDRLEAGTVFINTY--NKTDVAAPF 893

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2336	NP_731094.3	DUF1487	97..311	CDD:254173	42/171 (25%)
Aldh1l2	NP_001178707.2	FMT_core_FDH_N	23..225	CDD:187716
		FDH_Hydrolase_C	228..327	CDD:187731
		PP-binding	346..>390	CDD:395435
		ALDH_F1L_FTFDH	438..923	CDD:143458	42/171 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900