DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG2336 and ALDH1A3

DIOPT Version :9

Sequence 1:NP_731094.3 Gene:CG2336 / 40804 FlyBaseID:FBgn0037455 Length:322 Species:Drosophila melanogaster
Sequence 2:NP_000684.2 Gene:ALDH1A3 / 220 HGNCID:409 Length:512 Species:Homo sapiens


Alignment Length:210 Identity:43/210 - (20%)
Similarity:67/210 - (31%) Gaps:78/210 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly   105 ILCEDGDINCALHYLVESLHDPF------ACNAVATLFLQESILEEFVDRIRDRLEPLSTDISGH 163
            |:|.|.|::.|    ||..|...      .|.|.:.:|::|.:..|||.|        |.:.:  
Human   288 IVCADADLDLA----VECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRR--------SVEYA-- 338

  Fly   164 PVYIMTLERIGHLQAKRIVGNPKTVPENASPML-------VYDLSHRYLADG------------- 208
                          .||.||:|..|.....|.:       :.:|......:|             
Human   339 --------------KKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDK 389

  Fly   209 -----PT--GVITLHTFRTMKEAVELQAKEPLNFTSV----------------CIWNEKLAAAYE 250
                 ||  ..:| ...|..||.:....:..|.|.|:                .::.:.|..|.:
Human   390 GLFIKPTVFSEVT-DNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALK 453

  Fly   251 LVARLSPLIFTINCY 265
            |.:.|......||||
Human   454 LASALESGTVWINCY 468

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2336NP_731094.3 DUF1487 97..311 CDD:254173 43/210 (20%)
ALDH1A3NP_000684.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..22
ALDH_F1AB_F2_RALDH1 26..506 CDD:143459 43/210 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG1012
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.