DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2336 and alh-3

DIOPT Version :9

Sequence 1:	NP_731094.3	Gene:	CG2336 / 40804	FlyBaseID:	FBgn0037455	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_502054.2	Gene:	alh-3 / 177999	WormBaseID:	WBGene00000109	Length:	908	Species:	Caenorhabditis elegans

Alignment Length:	114	Identity:	23/114 - (20%)
Similarity:	45/114 - (39%)	Gaps:	29/114 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 EVQVKYQWNSPRLMILCEDGDINCALHYLVESLHDPFACNAV-----------ATLFLQESILEE 144
            :|.::....||  :|:..|.|:..|:..         ||.||           ..:|:.:||.::
Worm   675 KVSLELGGKSP--LIIFADADLEKAVKQ---------ACGAVFFNKGENCIAAGRVFIAKSIHDD 728

  Fly   145 FVDRIRDRL------EPLSTDISGHPV-YIMTLERIGHLQAKRIVGNPK 186
            ||.::.:..      :||....:..|. ::..|.::.....|.:.|..|
Worm   729 FVKKLVEEAKQYQIGDPLDRSTAHGPQNHLAHLNKLVEYVEKAVAGGAK 777

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2336	NP_731094.3	DUF1487	97..311	CDD:254173	22/108 (20%)
alh-3	NP_502054.2	fmt	1..318	CDD:273088
		FMT_core_FDH_N	1..209	CDD:187716
		FDH_Hydrolase_C	214..315	CDD:187731
		PP-binding	335..393	CDD:278949
		ALDH-SF	423..908	CDD:299846	23/114 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900