DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2336 and aldh1l2

DIOPT Version :9

Sequence 1:	NP_731094.3	Gene:	CG2336 / 40804	FlyBaseID:	FBgn0037455	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	XP_002661418.2	Gene:	aldh1l2 / 100333269	ZFINID:	ZDB-GENE-100426-6	Length:	923	Species:	Danio rerio

Alignment Length:	212	Identity:	48/212 - (22%)
Similarity:	90/212 - (42%)	Gaps:	34/212 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 EVQVKYQWNSPRLMILCEDGDINCALHYLVESLHDPF----ACNAVATLFLQESILEEFVDRIRD 151
            :|.::....||  :|:..|.|::.|:...:.|::  |    .|.|...||::|||.:|::.|:.:
Zfish   690 KVSLELGGKSP--LIIFSDCDMDKAVRMGMSSVY--FNKGENCIAAGRLFVEESIHDEYIRRVVE 750

  Fly   152 RL------EPL--STD--ISGHPVYIMTLE---RIGHLQAKRIVGNPKTVPENA---SPMLVYDL 200
            .:      :||  |||  ...|..::..|.   .||..:...:|...:.|....   .|.:..|:
Zfish   751 EIKKMKIGDPLDRSTDHGPQNHKAHMDKLVEYCEIGVKEGATLVYGGRQVDRPGFFMEPTVFTDV 815

  Fly   201 -SHRYLAD----GPTGVITLHTFRTMK-EAVELQAKEPLNFTSVCIWNEKLAAAYELVARLSPLI 259
             .|.::|.    ||  |:.:..|:... :.|..:|.:.....:..::...:..|..:..||....
Zfish   816 EDHMFIAKEESFGP--VMVVSKFKDGDVDGVLSRANDTEFGLASGVFTRDINKAMYVSERLEAGT 878

  Fly   260 FTINCYYVNLNEITLPF 276
            ..||.|  |..::..||
Zfish   879 VFINTY--NKTDVAAPF 893

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2336	NP_731094.3	DUF1487	97..311	CDD:254173	47/206 (23%)
aldh1l2	XP_002661418.2	Fmt	22..323	CDD:223301
		FMT_core_FDH_N	23..225	CDD:187716
		FDH_Hydrolase_C	228..327	CDD:187731
		PP-binding	346..412	CDD:278949
		ALDH_F1L_FTFDH	438..923	CDD:143458	48/212 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900