Protein Alignment CG1137 and IQCD

DIOPT Version :9

• Sequence 1: NP_649665.2
• Gene: CG1137 / 40803
• FlyBaseID: FBgn0037454
• Length: 379
• Species: Drosophila melanogaster
• Sequence 2: NP_001317381.1
• Gene: IQCD / 115811
• HGNCID: 25168
• Length: 449
• Species: Homo sapiens
• Alignment Length: 419
• Identity: 93/419 - (22%)
• Similarity: 187/419 - (44%)
• Gaps: 73/419 - (17%)

  Fly    13 PAEKKNDIKLAQHEFATVRIVQIGCVLNVLAEAIERVKISLIMPKLLEHPAHMAKILNGTKYEKA 77
            ||:....:.|::.:..|:...:|   :::|.|||.:|::..::..:..:...|..:| |....:|
Human    30 PADPLKPLVLSRTKLTTIEAKRI---MSILDEAIYKVELVTLLSYVASNREDMEGML-GEDVMRA 90

  Fly    78 VH--------LVESF--VRRREFILREKR----------------------PPLMDHGIIQIIDF 110
            |.        |:|:.  ::.:|..|:|::                      .|||.    ||.|.
Human    91 VREHEDLCQVLLENVRCLKEKERQLQEQKEAEEEGWLRDRLLSIELQKSSLSPLMQ----QIKDS 151

  Fly   111 FQRNSRIYLLFPSYYNHM-------SDNEKKLLNAFEMLYDLAKDRLYRTSTDAIAQERQLHAMY 168
            .:...|:.|..|.....:       |...:..:::...|.....::|..:..:|..:.:.|..:.
Human   152 TKNVLRLLLSNPQAARLLQMQTQGRSAEAQNFIDSLIELRGFLFEKLLTSPMEARDKAQFLQDIS 216

  Fly   169 KQNEVVKEQVEELRKKILDQKAAIRKSLADKEAY----LQNYEDLLMKKKREKNERIQKEIDRCT 229
            :||...::.::.|.|: |.::...|.:..:||.:    |:|:...::|.......|.::|.:
Human   217 RQNSNNQQIIDTLEKE-LAERMKNRNAEVEKENFVIQELKNHLHQVLKFSENSLVRTKQEAE--- 277

  Fly   230 RLVKANKKLSLERQADLEEQ-LQKTRNNYNLTTKNYLKQEKVFREEKNKLILQLQAIIKKYDHSI 293
            :..||:.:.|..|.|.:::: ||.....|||..:| .:.|:..|::|.|:..:::..|:|||..:
Human   278 KQQKADFRASQARVAKIQQEILQLQSQFYNLVMEN-REAEQALRKKKYKVETEIENWIQKYDTEM 341

  Fly   294 GEKMIENMELAEEHKKAKKALDEYMIGFLKVERVYKQIVVK----REEEEARHRQHRVL---LFA 351
            |||..|..:|...|::.|.:|:|       :.|.:|.:|.:    |||.|...::....   :..
Human   342 GEKQEELEDLDAVHREEKISLEE-------LRRRHKVLVGEFAQIREEREINSKKRMEAEQEMVR 399

  Fly   352 MNRAAIKIQKYWRKW--KKHMRKKNRRNK 378
            |.|||..||..|:.:  :..:|.|.:|.|
Human   400 MVRAATLIQALWKGYLVRSLLRSKKKRGK 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1137	NP_649665.2	Smc	<161..>375	CDD:224117	58/227 (26%)
IQCD	NP_001317381.1	Smc	<212..>396	CDD:224117	49/195 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	422..449		3/7 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56817
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR31598
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R9920
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	4	4.100