DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr11 and aebp1b

DIOPT Version :9

Sequence 1:	NP_001262320.1	Gene:	dpr11 / 40800	FlyBaseID:	FBgn0053202	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_696022.6	Gene:	aebp1b / 567630	ZFINID:	ZDB-GENE-030131-8546	Length:	1247	Species:	Danio rerio

Alignment Length:	237	Identity:	41/237 - (17%)
Similarity:	84/237 - (35%)	Gaps:	68/237 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 SATAFSSLAQVSSLLPEASALSATSGLVEPYLDGYATSNVTTQIGTHAYLPCRVKQLGNKSVSWI 152
            :.|:...|.||.              ::.||        .|.::|.|..|.|:|.. ..|:::|:
Zfish    48 NVTSVEDLLQVK--------------IIPPY--------ATIEVGQHKQLLCKVSS-DAKNINWV 89

  Fly   153 RLRDGHILTVDRAVFIADQRFLAIKQPDKYWTLQIKYVQARDAGSYECQVST--EPKVSARVQLQ 215
            ......:||....:.:.:...:..       :|.:......:||.|:| |:|  :.:..|.|:|.
Zfish    90 SPNGEKVLTKHGNLKVHNHGSVLS-------SLTVLNANLNNAGIYKC-VATNGDTESQATVKLD 146

  Fly   216 VVVPR----TEILGEPDRYVKAGSNVVLRCIVRGALEPPTFIMWYHGAEQLAADSRRHRTQLDPN 276
            :::.|    |:..|...|                 |:.|             ..|::.:......
Zfish   147 IILKRMRRDTDRKGREKR-----------------LKEP-------------KPSKKPKASKPTK 181

  Fly   277 LPEASGEGQSTIGSLIIESAKKRDTGNYTCSPSNSPSATVTL 318
            .|::..:|:...|.. .:..|.|:......:.:.:|:.||.:
Zfish   182 KPKSEKKGKGEKGGK-KKGKKNREESTTVATTTVAPTTTVPM 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr11	NP_001262320.1	I-set	125..216	CDD:254352	20/92 (22%)
		Ig	127..217	CDD:299845	20/91 (22%)
		IG_like	227..320	CDD:214653	12/92 (13%)
		IGc2	234..311	CDD:197706	8/76 (11%)
aebp1b	XP_696022.6	Ig	56..147	CDD:299845	24/121 (20%)
		IG_like	62..145	CDD:214653	21/99 (21%)
		FA58C	402..555	CDD:238014
		FA58C	403..556	CDD:214572
		Peptidase_M14_like	577..1036	CDD:299699
		Peptidase_M14NE-CP-C_like	1040..1115	CDD:200604
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900