DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpr11 and paplna

DIOPT Version :9

Sequence 1:	NP_001262320.1	Gene:	dpr11 / 40800	FlyBaseID:	FBgn0053202	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_005169942.1	Gene:	paplna / 562930	ZFINID:	ZDB-GENE-070815-4	Length:	1187	Species:	Danio rerio

Alignment Length:	283	Identity:	65/283 - (22%)
Similarity:	101/283 - (35%)	Gaps:	83/283 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 AGTSSASAASTAISSDESGDPSSATAFSSLAQVSSLLPEASALSATSGLVEPYLDGYATSNVTTQ 130
            :|:|..:|..:.:.|.:|....|::.|:               ...|.|||            .:
Zfish   921 SGSSQNNAGISEVDSSQSYTSQSSSRFN---------------IDYSPLVE------------AR 958

  Fly   131 IGTHAYLPCR---VKQLGNKSVSWIRLRDGHILTVDRAVFIADQRFLAIKQPD-KYWTLQIKYVQ 191
            .|..|.|.|.   |..:...::.|.|               |.|...:::... ...||.||.:.
Zfish   959 AGQTAKLQCSVLPVSAIHAVTIHWSR---------------AGQPLNSLRHSQHSDGTLVIKQLT 1008

  Fly   192 ARDAGSYECQVSTEPKVSAR-VQLQVV----VPRTEILGEPDRYVKAGSNVVLRCIVRGALEPPT 251
            |.|:|.|.|.|:...|...| |||:|:    :.:..|    |..|..||...|.|:|.|   ...
Zfish  1009 ADDSGLYTCTVTDAQKFEERQVQLRVLGDLRITKAPI----DVDVVQGSTAQLACVVTG---ENV 1066

  Fly   252 FIMWYHGAEQLAADSRRHRTQLDPNLPEASGEGQSTIGSLIIESAKKRDTGNYTCSP-----SNS 311
            .:.|......:..|..|.....|              |:||:.:.:..|.|.|||:.     |.|
Zfish  1067 NVGWSRNGVPVRPDGHRVHVSAD--------------GTLILNNVQSVDEGTYTCNAYTGTLSVS 1117

  Fly   312 PSATVTL------NIINGESSAS 328
            .:|.:.|      :|..|:.|:|
Zfish  1118 AAAEIRLAKTPQQDIDGGQFSSS 1140

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr11	NP_001262320.1	I-set	125..216	CDD:254352	24/95 (25%)
		Ig	127..217	CDD:299845	24/94 (26%)
		IG_like	227..320	CDD:214653	24/103 (23%)
		IGc2	234..311	CDD:197706	19/81 (23%)
paplna	XP_005169942.1	TSP1	24..75	CDD:214559
		ADAM_spacer1	181..293	CDD:310520
		TSP1	303..356	CDD:214559
		TSP1	388..442	CDD:214559
		TSP1	449..498	CDD:214559
		TSP1	504..557	CDD:214559
		KU	720..771	CDD:238057
		Ig_3	839..906	CDD:316449
		IGc2	960..1022	CDD:197706	19/76 (25%)
		I-set	1039..1121	CDD:333254	23/102 (23%)
		PLAC	1142..1173	CDD:312271
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900