DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr11 and sdk1a

DIOPT Version :9

Sequence 1:	NP_001262320.1	Gene:	dpr11 / 40800	FlyBaseID:	FBgn0053202	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_009297968.1	Gene:	sdk1a / 558391	ZFINID:	ZDB-GENE-081104-374	Length:	2245	Species:	Danio rerio

Alignment Length:	294	Identity:	80/294 - (27%)
Similarity:	112/294 - (38%)	Gaps:	56/294 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 AISSDESGDPSSATAFSSLAQVSSLLPEASAL-------SATSGLVEPYLDGYATS--------- 125
            |:...:..:|......|...||..|.|..:.:       ||....|..|||  .||
Zfish   454 AVPLSKLNNPRYKIISSMGLQVRKLQPSDAGIFQCFARNSAGEAQVHTYLD--VTSMAPAFTAPP 516

  Fly   126 -NVTTQIGTHAYLPCRVKQLGNKSVSWIRLRDGHILTVDRAVFIADQRFLAIKQPDKYWTLQIKY 189
             ::|...|..|...|||......::.|  .||..||.   :..:...||..::...    |||:.
Zfish   517 LDITVTDGAVAAFTCRVSGAPKPAIVW--RRDTQILA---SGSVQIPRFTLLESGG----LQIQP 572

  Fly   190 VQARDAGSYEC-QVSTEPKVSARVQLQVVVPRTEILGEP-DRYVKAGSNVVLRCIVRGALEPPTF 252
            |..:|.|:|.| ..::|..::|...| .|..||.|...| ||.|..|:..:|.|   ||...|..
Zfish   573 VVLQDTGNYTCYAANSEGAINASASL-TVWSRTSISSPPTDRRVIKGTTAILEC---GATHDPRV 633

  Fly   253 ---IMWYHGAEQLAADSRRHRTQLDPNLPEASGEGQSTIGSLIIESAKKRDTGNYTC---SPSNS 311
               .:|... |:|.:.||..|..|..             |||.|......|.|||||   |.:.:
Zfish   634 GVRYVWKKD-EELVSHSRGGRISLQE-------------GSLHISQTWSGDIGNYTCDVISEAGN 684

  Fly   312 PSATVTLNIINGESSASAVTSS--AATTRAYALS 343
            .|....|.:|....|...:.:|  |..:|:..||
Zfish   685 ESKEARLEVIELPHSPRNLQASLNANDSRSVDLS 718

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr11	NP_001262320.1	I-set	125..216	CDD:254352	25/101 (25%)
		Ig	127..217	CDD:299845	24/90 (27%)
		IG_like	227..320	CDD:214653	30/99 (30%)
		IGc2	234..311	CDD:197706	24/82 (29%)
sdk1a	XP_009297968.1	I-set	125..208	CDD:254352
		Ig	125..204	CDD:299845
		IG_like	222..302	CDD:214653
		Ig	236..287	CDD:299845
		Ig_3	322..394	CDD:290638
		I-set	323..412	CDD:254352
		I-set	416..505	CDD:254352	13/52 (25%)
		Ig	436..500	CDD:299845	9/45 (20%)
		I-set	510..600	CDD:254352	24/99 (24%)
		Ig	527..600	CDD:299845	22/82 (27%)
		I-set	605..693	CDD:254352	31/104 (30%)
		Ig	610..693	CDD:299845	30/99 (30%)
		FN3	697..788	CDD:238020	6/22 (27%)
		fn3	800..886	CDD:278470
		FN3	901..997	CDD:238020
		FN3	1002..1090	CDD:238020
		FN3	1100..1196	CDD:238020
		FN3	1206..1301	CDD:238020
		FN3	1308..1397	CDD:238020
		FN3	1408..1501	CDD:238020
		FN3	1507..1602	CDD:238020
		FN3	1616..1722	CDD:238020
		FN3	1732..1825	CDD:238020
		FN3	1830..1919	CDD:238020
		FN3	1931..2021	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810