DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpr11 and KIRREL1

DIOPT Version :9

Sequence 1:	NP_001262320.1	Gene:	dpr11 / 40800	FlyBaseID:	FBgn0053202	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_005245362.1	Gene:	KIRREL1 / 55243	HGNCID:	15734	Length:	773	Species:	Homo sapiens

Alignment Length:	215	Identity:	63/215 - (29%)
Similarity:	93/215 - (43%)	Gaps:	38/215 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 TTQIGTHAYLPCRVKQLGNKS--VSWIRLRDGHILTVDRAVFIADQRFLAIKQPDK-YWTLQIKY 189
            |...|..|.|||   .|.|.|  |.|  .:||..|.:.:.: .|..|:..:...|. .:.|:|..
Human    31 TVVAGQRAVLPC---VLLNYSGIVQW--TKDGLALGMGQGL-KAWPRYRVVGSADAGQYNLEITD 89

  Fly   190 VQARDAGSYECQVSTEPKVSARVQLQVVVP--RTEILGEPDRYVKAGSNVVLRCIVRGALEPPTF 252
            .:..|..|||||.:.....|.|.:|.|::|  .|.|.|.|...::||:...|.|....| :|...
Human    90 AELSDDASYECQATEAALRSRRAKLTVLIPPEDTRIDGGPVILLQAGTPHNLTCRAFNA-KPAAT 153

  Fly   253 IMWYH-GAEQLAADSRRHRTQLDPNLPEASGEGQSTIGSLIIESAKKRDTGN-YTCSPSNS--PS 313
            |:|:. |.:|..|.:   .|:|     ...|:.::|:..|:| :....|.|. :||...|.  ||
Human   154 IIWFRDGTQQEGAVA---STEL-----LKDGKRETTVSQLLI-NPTDLDIGRVFTCRSMNEAIPS 209

  Fly   314 A-------------TVTLNI 320
            .             ||||:|
Human   210 GKETSIELDVHHPPTVTLSI 229

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr11	NP_001262320.1	I-set	125..216	CDD:254352	28/90 (31%)
		Ig	127..217	CDD:299845	28/91 (31%)
		IG_like	227..320	CDD:214653	29/109 (27%)
		IGc2	234..311	CDD:197706	20/78 (26%)
KIRREL1	XP_005245362.1	I-set	22..116	CDD:254352	28/90 (31%)
		Ig	25..116	CDD:299845	28/90 (31%)
		Ig2_KIRREL3-like	138..219	CDD:143236	22/90 (24%)
		I-set	223..304	CDD:254352	5/7 (71%)
		Ig_2	227..305	CDD:290606	2/3 (67%)
		Ig_2	311..405	CDD:290606
		IG_like	314..405	CDD:214653
		Ig5_KIRREL3	407..504	CDD:143306
		IG_like	416..504	CDD:214653
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810