DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpr11 and iglon5

DIOPT Version :9

Sequence 1:	NP_001262320.1	Gene:	dpr11 / 40800	FlyBaseID:	FBgn0053202	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_001017775.2	Gene:	iglon5 / 550472	ZFINID:	ZDB-GENE-050417-297	Length:	332	Species:	Danio rerio

Alignment Length:	318	Identity:	67/318 - (21%)
Similarity:	107/318 - (33%)	Gaps:	107/318 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   121 GYATSNVTTQIGTHAYLPCRV-KQLGNKSVSWIRLRDGHILTVDRAVFIADQRFLAIKQPDKYWT 184
            |:...|:|...|....|.|:: :::.:|  :|  |...:||......:..|.|.......:..::
Zfish    30 GHLPDNITVLEGESVVLRCKIDEEVTHK--AW--LNRSNILFTGTDKWSLDSRVSLENNNNSDFS 90

  Fly   185 LQIKYVQARDAGSYEC--QVSTEPKVSARVQLQVVVPRTEILGEPDRYVKAGSNVVLRCIVRGAL 247
            ::|:.|...|.|.|.|  |...:|: :|.|.|.|.||...:....|:.|..|.:|.|.|:..|..
Zfish    91 IRIERVMVADEGPYTCSFQARNKPR-TAHVYLIVQVPARIVNISQDKSVNEGEDVNLFCLAVGRP 154

  Fly   248 EPPTFIMW--------------------YHGAEQLAA---------DSRRHRTQLD--------P 275
            ||.  |.|                    .|.||....         |:|:.:..::        .
Zfish   155 EPT--ITWKDFKYGLLNEGEFLEITEIKRHQAEDFECITNNGVAPPDTRKVKVTVNYPPIITDVK 217

  Fly   276 NLPEASG-----------------------------------EGQSTIGSLIIESAKKRDTGNYT 305
            |:|...|                                   :.:.|...|:..:..::..||||
Zfish   218 NMPAQVGKTAILRCEAMAVPTASFEWYRDDRRPVESDNTLKIKNEKTRSLLLFTNVTEKHFGNYT 282

  Fly   306 CSPSNSPSATVTLNIINGESSAS-------AVTSSAATTRA--------YALSILALL 348
            |..||.          .|.|:||       ||...||:...        :.|||..|:
Zfish   283 CFASNR----------LGASNASMLLFRPGAVYGGAASLNGRLSGVGLWFCLSISVLM 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr11	NP_001262320.1	I-set	125..216	CDD:254352	23/93 (25%)
		Ig	127..217	CDD:299845	22/92 (24%)
		IG_like	227..320	CDD:214653	28/164 (17%)
		IGc2	234..311	CDD:197706	25/148 (17%)
iglon5	NP_001017775.2	IG_like	33..123	CDD:214653	23/94 (24%)
		Ig	35..123	CDD:299845	23/92 (25%)
		Ig	125..>183	CDD:299845	13/59 (22%)
		I-set	128..207	CDD:254352	16/80 (20%)
		IG_like	217..298	CDD:214653	16/90 (18%)
		ig	223..296	CDD:278476	13/82 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910