Protein Alignment dpr11 and NTM

DIOPT Version :10

• Sequence 1: NP_788586.1
• Gene: dpr11 / 40800
• FlyBaseID: FBgn0053202
• Length: 360
• Species: Drosophila melanogaster
• Sequence 2: NP_001338930.1
• Gene: NTM / 50863
• HGNCID: 17941
• Length: 367
• Species: Homo sapiens
• Alignment Length: 353
• Identity: 80/353 - (22%)
• Similarity: 126/353 - (35%)
• Gaps: 112/353 - (31%)

  Fly   106 SALSATSGLVEPYLDGYAT-----SNVTTQIGTHAYLPCRVKQLGNKSVSWIRLRDGHILTVDRA 165
            :||....|:  |...|.||     .|||.:.|..|.|.|.:.....: |:|  |....||.....
Human    21 AALCLFQGV--PVRSGDATFPKAMDNVTVRQGESATLRCTIDNRVTR-VAW--LNRSTILYAGND 80

  Fly   166 VFIADQRFLAIKQPDKYWTLQIKYVQARDAGSYECQVSTE--PKVSARVQLQVVVPRTEILGEPD 228
            .:..|.|.:.:......::::|:.|...|.|.|.|.|.|:  ||.| ||.|.|.|....:....|
Human    81 KWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTS-RVHLIVQVSPKIVEISSD 144

  Fly   229 RYVKAGSNVVLRCIVRGALEPPTFIMWYH-------------------------GAEQLAADS-- 266
            ..:..|:|:.|.||..|..||.  :.|.|                         |..:.:|.:
Human   145 ISINEGNNISLTCIATGRPEPT--VTWRHISPKAVGFVSEDEYLEIQGITREQSGDYECSASNDV 207

  Fly   267 -----RRHRTQLD--PNLPEASG-----------------------------------------E 283
                 ||.:..::  |.:.||.|                                         |
Human   208 AAPVVRRVKVTVNYPPYISEAKGTGVPVGQKGTLQCEASAVPSAEFQWYKDDKRLIEGKKGVKVE 272

  Fly   284 GQSTIGSLIIESAKKRDTGNYTCSPSNS---PSATVTLNIINGESSA--------SAVT------ 331
            .:..:..||..:..:.|.|||||..||.   .:|::.|..:|..:|:        :|:|
Human   273 NRPFLSKLIFFNVSEHDYGNYTCVASNKLGHTNASIMLFELNEPTSSTLLQEVKTTALTPWKGPG 337

  Fly   332 -----SSAATTRAYALSILALLLSVILI 354
                 |:..:.||..:.:|.||:..:|:
Human   338 AVSEVSNGTSRRAGCVWLLPLLVLHLLL 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpr11	NP_788586.1	Ig	125..216	CDD:472250	28/92 (30%)
		Ig strand B	135..139	CDD:409353	2/3 (67%)
		Ig strand C	148..152	CDD:409353	1/3 (33%)
		Ig strand E	183..187	CDD:409353	0/3 (0%)
		Ig strand F	197..202	CDD:409353	2/4 (50%)
		IG_like	227..320	CDD:214653	32/170 (19%)
		Ig strand B	237..241	CDD:409544	1/3 (33%)
		Ig strand C	252..256	CDD:409544	0/3 (0%)
		Ig strand E	289..293	CDD:409544	1/3 (33%)
		Ig strand G	313..316	CDD:409544	1/2 (50%)
NTM	NP_001338930.1	Ig	44..132	CDD:472250	28/91 (31%)
		Ig strand B	53..57	CDD:409353	2/3 (67%)
		Ig strand C	65..69	CDD:409353	2/6 (33%)
		Ig strand E	98..102	CDD:409353	0/3 (0%)
		Ig strand F	112..117	CDD:409353	2/4 (50%)
		Ig strand G	125..128	CDD:409353	1/3 (33%)
		Ig_3	136..205	CDD:464046	13/70 (19%)
		Ig	223..307	CDD:472250	15/83 (18%)
		Ig strand B	239..243	CDD:409353	0/3 (0%)
		Ig strand C	252..256	CDD:409353	0/3 (0%)
		Ig strand E	278..282	CDD:409353	1/3 (33%)
		Ig strand F	292..297	CDD:409353	4/4 (100%)