DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr11 and cadm2

DIOPT Version :9

Sequence 1:NP_001262320.1 Gene:dpr11 / 40800 FlyBaseID:FBgn0053202 Length:360 Species:Drosophila melanogaster
Sequence 2:XP_031751706.1 Gene:cadm2 / 448238 XenbaseID:XB-GENE-998536 Length:441 Species:Xenopus tropicalis


Alignment Length:411 Identity:82/411 - (19%)
Similarity:121/411 - (29%) Gaps:167/411 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly    95 LAQVSSLLPEASALSATSGLV---------EPYLDGY-ATSNVTTQIGTHAYLPCRVKQLGNKSV 149
            :.|.|:||    .||:..|::         :|....: .|.|||...|....|.|||.|..|.|:
 Frog     2 ILQPSALL----CLSSLWGVIVQAASPRNKKPSQGQFPVTQNVTVVEGGTINLTCRVDQNDNTSL 62

  Fly   150 SWIRLRDGHILTVDRAVFIADQRFLAIKQPDKYWTLQIKYVQARDAGSYECQVSTEPKVSARVQL 214
            .|..... ..|..|....:.|.|...::......::.|..|...|.|.|.|.:.|.|..:::..|
 Frog    63 QWSNPAQ-QTLYFDDKKALRDNRIELVRASWHELSISISDVSLSDEGQYTCSLFTMPVKTSKAYL 126

  Fly   215 QVV-VPRTEILGEPDRYVKAGSNVVLRCIVRGALEPPTFIMWYHGAEQLAADSRRHRTQLDPN-- 276
            .|: ||....:......|..|..:.|.|...|: :|...|.|:...::: .|.::.:.| |.|  
 Frog   127 MVLGVPENPHISGFTSPVMEGDTIQLTCKSSGS-KPAADIRWFKNDQEI-TDVQKIQQQ-DSNGK 188

  Fly   277 --------------------------------------------------------LPEASGEGQ 285
                                                                    ||:   |||
 Frog   189 TFTVTSSLVFQGDRKDDGAVIRCRVDHESLTSTPQIAKQVLEIHYTPTVRILPSTPLPQ---EGQ 250

  Fly   286 STIGSLIIES-----------------------------------AKKRDTGNYTCSPSNS---- 311
            ..|  ||.||                                   ..|.|.|.|.|..:||    
 Frog   251 PLI--LICESKGKPLPEPVLWTKDGGELPDPERMTVNGRELTISFLNKTDNGTYRCEATNSIGQS 313

  Fly   312 ------------------------PSATVTLNIINGESSASAVTSSAATTR-------------- 338
                                    .||||..|:    :.::..|.||..|:              
 Frog   314 SAEYVLIINDVPKPLFPTTIIPLFTSATVKTNV----AMSTRTTKSAFITKDPNALPGPVATDHA 374

  Fly   339 ----AYALSILALLLSVILIG 355
                ..|:.:...|.|:||||
 Frog   375 LIGGVVAVVVFVTLCSIILIG 395

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr11NP_001262320.1 I-set 125..216 CDD:254352 25/90 (28%)
Ig 127..217 CDD:299845 24/89 (27%)
IG_like 227..320 CDD:214653 33/213 (15%)
IGc2 234..311 CDD:197706 26/169 (15%)
cadm2XP_031751706.1 IgV_1_Necl-3 34..129 CDD:409498 26/95 (27%)
Ig strand B 48..52 CDD:409498 1/3 (33%)
Ig strand C 61..65 CDD:409498 1/3 (33%)
Ig strand E 95..99 CDD:409498 0/3 (0%)
Ig strand F 109..114 CDD:409498 2/4 (50%)
Ig strand G 121..124 CDD:409498 0/2 (0%)
IgI_2_Necl-3 128..231 CDD:409467 15/105 (14%)
Ig strand B 150..154 CDD:409467 1/3 (33%)
Ig strand C 164..168 CDD:409467 1/3 (33%)
Ig strand E 194..198 CDD:409467 0/3 (0%)
Ig strand F 208..213 CDD:409467 0/4 (0%)
Ig strand G 224..227 CDD:409467 0/2 (0%)
IGc2 248..311 CDD:197706 15/64 (23%)
Ig strand B 250..259 CDD:409353 5/10 (50%)
Ig strand C 265..271 CDD:409353 0/5 (0%)
Ig strand C' 274..277 CDD:409353 0/2 (0%)
Ig strand D 280..285 CDD:409353 0/4 (0%)
Ig strand E 286..293 CDD:409353 0/6 (0%)
Ig strand F 300..308 CDD:409353 3/7 (43%)
Ig strand G 311..321 CDD:409353 0/9 (0%)
4.1m 394..412 CDD:128590 2/2 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 82 1.000 Inparanoid score I5030
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.960

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