DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr11 and klg

DIOPT Version :9

Sequence 1:	NP_001262320.1	Gene:	dpr11 / 40800	FlyBaseID:	FBgn0053202	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_524454.2	Gene:	klg / 42707	FlyBaseID:	FBgn0017590	Length:	545	Species:	Drosophila melanogaster

Alignment Length:	324	Identity:	83/324 - (25%)
Similarity:	125/324 - (38%)	Gaps:	91/324 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 GILCLTIASHTQTSAEAAGGRVSGP-------------------GAGTSEGAGTSSASAASTAIS 79
            |.|...|.:|...:|.|:|.|.|..                   |......|| |...|...|||
  Fly    11 GALAPPITAHASANANASGLRKSSQRRNRAPLQMNCPILIVISLGWLLHAHAG-SGGFAVEAAIS 74

  Fly    80 SDESGDPSSATAFSSLAQVSSLLPEASALSATSGLVEPYLDGYATSNVTTQ--IGTHAYLPCRVK 142
            :..|..       .|::.|......||.|:||       |..:.:...|.:  :|....|||:|:
  Fly    75 NRGSNS-------RSMSNVQQSAVAASTLTAT-------LPRFLSRGHTYRAVVGDTLVLPCQVE 125

  Fly   143 QLGNKSVSWIRLRDGHILTVDRAVFIADQRFLAIKQPDKYWTLQIKYVQARDAGSYECQVSTEPK 207
            .|||..:.|  .|..::||....:...|:|   ::..|.| .|:|..::.:|||.|.||:|  .|
  Fly   126 NLGNFVLLW--RRGTNVLTASNIMVTRDER---VRLIDGY-NLEISDLEPQDAGDYVCQIS--DK 182

  Fly   208 VSARVQLQVVVPRTEILGEPDRYVKA-----------GSNVVLRCIVRGALEPPTFIMWYHGAEQ 261
            :: |.|:..|    |||..|.  |:|           |..:.|.|  :|:..|...|.|
  Fly   183 IN-RDQVHTV----EILVPPS--VRAIPTSGQLQARKGGPITLEC--KGSGNPVPSIYW------ 232

  Fly   262 LAADSRRHRTQLDPNLPEASGEGQST--IGS---LIIESAKKRDTGNYTCSPSNSPSATVTLNI 320
                            .:.||..:||  ||.   |.:|..:::..|.|.|:..|.....||:::
  Fly   233 ----------------TKKSGANKSTARIGDGPILTLEKLERQQAGVYQCTADNGVGDPVTVDM 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr11	NP_001262320.1	I-set	125..216	CDD:254352	29/92 (32%)
		Ig	127..217	CDD:299845	29/91 (32%)
		IG_like	227..320	CDD:214653	24/108 (22%)
		IGc2	234..311	CDD:197706	18/81 (22%)
klg	NP_524454.2	DUF1370	63..>124	CDD:284518	20/75 (27%)
		IG_like	109..195	CDD:214653	32/98 (33%)
		Ig	118..191	CDD:143165	27/81 (33%)
		IG_like	205..274	CDD:214653	19/92 (21%)
		IGc2	213..273	CDD:197706	19/83 (23%)
		IGc2	301..367	CDD:197706
		FN3	392..486	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810