DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr11 and kirrel1a

DIOPT Version :9

Sequence 1:	NP_001262320.1	Gene:	dpr11 / 40800	FlyBaseID:	FBgn0053202	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_001349348.1	Gene:	kirrel1a / 405804	ZFINID:	ZDB-GENE-040426-2126	Length:	819	Species:	Danio rerio

Alignment Length:	237	Identity:	58/237 - (24%)
Similarity:	90/237 - (37%)	Gaps:	57/237 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 AQVSSLLPEASALSAT----SGLVEPYLDGYATSNVTTQIGTHAYLPCRVKQLGNKSVSWIRLRD 156
            |..|.:|.:...||..    ||:|:...||.|..                  :|....:|.|.|.
Zfish    27 ADQSVVLGQRVVLSCVVFNYSGIVQWTKDGLALG------------------IGEDLRAWPRYRV 73

  Fly   157 GHILTVDRAVFIADQRFLAIKQPDKYWTLQIKYVQARDAGSYECQVSTEPKVSARVQLQVVVPRT 221
            ..::.|.:                  :.|:|...:..|...||||.:.....|.|.:|.|::|..
Zfish    74 LRLVDVGQ------------------YNLEISAAELSDDSLYECQATEAALRSRRAKLTVLIPPD 120

  Fly   222 E--ILGEPDRYVKAGSNVVLRCIVRGALEPPTFIMWYHGAEQLAADSRRHRTQLDPNLPEASGEG 284
            |  |.|.|:..:.||....:.|:.||| :|.:.|.|.  .:.|..:.....|::.|:....:...
Zfish   121 EPVIEGSPEILLTAGVPYNMSCVSRGA-KPASVIEWQ--KDGLPIEGAVSTTEVLPDRKRVTTRS 182

  Fly   285 QSTIGSLIIESAKKRDTG-NYTCSPSN-----SPSATVTLNI 320
            ...|..|      ..||| |:||..:|     ...||:|||:
Zfish   183 YLPIQPL------DTDTGKNFTCVATNLAVPMGKRATITLNV 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr11	NP_001262320.1	I-set	125..216	CDD:254352	15/90 (17%)
		Ig	127..217	CDD:299845	15/89 (17%)
		IG_like	227..320	CDD:214653	26/98 (27%)
		IGc2	234..311	CDD:197706	20/82 (24%)
kirrel1a	NP_001349348.1	I-set	21..115	CDD:333254	26/123 (21%)
		Ig2_KIRREL3-like	137..218	CDD:143236	23/89 (26%)
		I-set	222..303	CDD:333254
		Ig_3	307..372	CDD:316449
		Ig5_KIRREL3	390..493	CDD:143306
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910