DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr11 and Dscam2

DIOPT Version :9

Sequence 1:	NP_001262320.1	Gene:	dpr11 / 40800	FlyBaseID:	FBgn0053202	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_001261500.1	Gene:	Dscam2 / 38788	FlyBaseID:	FBgn0265296	Length:	2101	Species:	Drosophila melanogaster

Alignment Length:	275	Identity:	66/275 - (24%)
Similarity:	91/275 - (33%)	Gaps:	92/275 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   103 PEASALSATS----GLVEPYLDGYATSNVTTQIGTHAYLPCRVKQLGNKSVSWIRLRDGHILTVD 163
            ||.....||:    |...|.| .|:....|.|.|....|.|.........:||         |:|
  Fly   405 PEGDTFQATAELQLGDAPPVL-LYSFIEQTLQPGPAVSLKCSAAGNPTPQISW---------TLD 459

  Fly   164 RAVFIADQRFLAIKQPDKYWT--------LQIKYVQARDAGSYECQVSTEPKVSARVQLQVVVPR 220
            .....::.||:.    .:|.|        :.|.:|...|.|.|.|.....   :.|||   ...|
  Fly   460 GFPLPSNGRFMI----GQYITVHGDVISHVNISHVMVEDGGEYACIAENR---AGRVQ---HAAR 514

  Fly   221 TEILGEPDRYVK--------AGSNVVLRCIVRGALEPPTFIMWYHGAEQLAADSRRHRTQLDPNL 277
            ..|.|.|  |::        :|..:.|:|.|.|  .|...|.|..|..:| .|..|.|.|.|
  Fly   515 LNIYGLP--YIRLIPKVTAVSGETLNLKCPVAG--YPIEEIHWERGGREL-PDDIRQRVQPD--- 571

  Fly   278 PEASGEGQSTIGSLIIESAKKR-DTGNYTC--------------------SPSNSP--------- 312
                       |||.|...:|. |:|.|||                    .|..||
  Fly   572 -----------GSLTISPVQKNSDSGVYTCWARNKQGHSARRSGEVTVIVPPKLSPFQTNILQLN 625

  Fly   313 ---SATVTLNIINGE 324
               .|::|.:::.|:
  Fly   626 MGDRASLTCSVVKGD 640

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr11	NP_001262320.1	I-set	125..216	CDD:254352	22/98 (22%)
		Ig	127..217	CDD:299845	22/97 (23%)
		IG_like	227..320	CDD:214653	32/133 (24%)
		IGc2	234..311	CDD:197706	26/97 (27%)
Dscam2	NP_001261500.1	Ig	51..127	CDD:299845
		Ig	138..>203	CDD:299845
		I-set	238..327	CDD:254352
		Ig	247..327	CDD:299845
		I-set	332..418	CDD:254352	4/12 (33%)
		IGc2	344..407	CDD:197706	1/1 (100%)
		IG_like	432..517	CDD:214653	23/103 (22%)
		IGc2	436..507	CDD:197706	17/86 (20%)
		I-set	521..610	CDD:254352	27/107 (25%)
		IGc2	533..597	CDD:197706	25/80 (31%)
		Ig	630..699	CDD:143165	3/11 (27%)
		IG_like	714..802	CDD:214653
		Ig	725..802	CDD:299845
		Ig	823..894	CDD:143165
		FN3	906..1006	CDD:238020
		FN3	1013..1111	CDD:238020
		FN3	1119..1209	CDD:238020
		FN3	1219..1313	CDD:238020
		Ig	1336..1402	CDD:143165
		FN3	1409..1498	CDD:238020
		FN3	1515..1588	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810