DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr11 and Opcml

DIOPT Version :9

Sequence 1:NP_001262320.1 Gene:dpr11 / 40800 FlyBaseID:FBgn0053202 Length:360 Species:Drosophila melanogaster
Sequence 2:XP_006510497.1 Gene:Opcml / 330908 MGIID:97397 Length:354 Species:Mus musculus


Alignment Length:312 Identity:73/312 - (23%)
Similarity:106/312 - (33%) Gaps:107/312 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   117 PYLDGYAT-----SNVTTQIGTHAYLPCRVKQLGNKSVSWIRLRDGHILTVDRAVFIADQRFLAI 176
            |...|.||     .|||.:.|..|.|.|.:.....: |:|  |....||......:..|.|.:.:
Mouse    30 PVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTR-VAW--LNRSTILYAGNDKWSIDPRVIIL 91

  Fly   177 KQPDKYWTLQIKYVQARDAGSYECQVSTE--PKVSARVQLQVVVPRTEILGEPDRYVKAGSNVVL 239
            ......:::.|:.|...|.|.|.|.|.|:  ||.| ||.|.|.||...:....|..|..||:|.|
Mouse    92 VNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTS-RVHLIVQVPPQIMNISSDITVNEGSSVTL 155

  Fly   240 RCIVRGALEPPTFIMWYH--------------------------------GAEQLAADSRRHRTQ 272
            .|:..|..||.  :.|.|                                ....:||...| :.:
Mouse   156 LCLAIGRPEPT--VTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVR-KVK 217

  Fly   273 LDPNLP---------------------EASG------------------------EGQSTIGSLI 292
            :..|.|                     |||.                        |.:..|.:|.
Mouse   218 ITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEDTRLATGLDGVRIENKGRISTLT 282

  Fly   293 IESAKKRDTGNYTCSPSN---SPSATVTL-------------NIINGESSAS 328
            ..:..::|.|||||..:|   :.:|::||             .:|:|.:|||
Mouse   283 FFNVSEKDYGNYTCVATNKLGNTNASITLYEISPSSAVAGPGAVIDGVNSAS 334

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr11NP_001262320.1 I-set 125..216 CDD:254352 28/92 (30%)
Ig 127..217 CDD:299845 27/91 (30%)
IG_like 227..320 CDD:214653 33/185 (18%)
IGc2 234..311 CDD:197706 28/156 (18%)
OpcmlXP_006510497.1 Ig 44..132 CDD:416386 28/91 (31%)
Ig strand A' 44..49 CDD:409353 3/4 (75%)
Ig strand B 51..59 CDD:409353 3/7 (43%)
CDR1 59..63 CDD:409353 0/3 (0%)
FR2 64..70 CDD:409353 2/8 (25%)
Ig strand C 64..70 CDD:409353 2/8 (25%)
CDR2 71..83 CDD:409353 2/11 (18%)
Ig strand C' 72..76 CDD:409353 1/3 (33%)
Ig strand C' 80..83 CDD:409353 0/2 (0%)
FR3 84..118 CDD:409353 8/33 (24%)
Ig strand D 87..94 CDD:409353 1/6 (17%)
Ig strand E 97..103 CDD:409353 0/5 (0%)
Ig strand F 110..118 CDD:409353 3/7 (43%)
CDR3 119..123 CDD:409353 1/3 (33%)
Ig strand G 123..132 CDD:409353 6/9 (67%)
FR4 125..132 CDD:409353 4/7 (57%)
Ig_3 135..206 CDD:404760 13/72 (18%)
Ig strand A 135..138 CDD:409353 1/2 (50%)
Ig strand A' 144..148 CDD:409353 1/3 (33%)
Ig strand B 151..160 CDD:409353 4/8 (50%)
Ig strand C 165..170 CDD:409353 1/6 (17%)
Ig strand C' 171..174 CDD:409353 1/2 (50%)
Ig strand F 198..206 CDD:409353 0/7 (0%)
Ig_3 223..300 CDD:404760 13/76 (17%)
putative Ig strand A 224..230 CDD:409353 0/5 (0%)
Ig strand B 240..244 CDD:409353 0/3 (0%)
Ig strand C 253..257 CDD:409353 0/3 (0%)
Ig strand E 279..283 CDD:409353 1/3 (33%)
Ig strand F 293..298 CDD:409353 4/4 (100%)
Ig strand G 306..309 CDD:409353 1/2 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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