DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr11 and Negr1

DIOPT Version :9

Sequence 1:NP_001262320.1 Gene:dpr11 / 40800 FlyBaseID:FBgn0053202 Length:360 Species:Drosophila melanogaster
Sequence 2:XP_036019026.1 Gene:Negr1 / 320840 MGIID:2444846 Length:362 Species:Mus musculus


Alignment Length:353 Identity:86/353 - (24%)
Similarity:132/353 - (37%) Gaps:110/353 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    95 LAQVSSLLPEASALSATSGLVEPYLDGYATSNVTTQIGTHAYLPCRVKQLGNKSVSWIR-----L 154
            ||.|  ||...|.|.|...:..|:.   |..|:..:.|..|.|.|.::...:|. :|:.     .
Mouse    15 LAAV--LLSLCSCLPAGQSVDFPWA---AVDNMLVRKGDTAVLRCYLEDGASKG-AWLNRSSIIF 73

  Fly   155 RDGHILTVDRAVFIADQRFLAIKQPDKYWTLQIKYVQARDAGSYECQVSTE--PKVSARVQLQVV 217
            ..|...:||..|.|:     .:.:.|  ::|||:.|...|.|.|.|.|.|:  |: :.:|.|.|.
Mouse    74 AGGDKWSVDPRVSIS-----TLNKRD--YSLQIQNVDVTDDGPYTCSVQTQHTPR-TMQVHLTVQ 130

  Fly   218 VPRTEILGEPDRYVKAGSNVVLRCIVRGALEPPTFIMWYH------------------------G 258
            ||........|..:..|:||.|.|:..|..||  .|.|.|                        |
Mouse   131 VPPKIYDISNDMTINEGTNVTLTCLATGKPEP--VISWRHISPSAKPFENGQYLDIYGITRDQAG 193

  Fly   259 AEQLAA-------DSRRHRTQLD--PNL---------PEASG----------------------- 282
            ..:.:|       |.::.|..::  |.:         |..||                       
Mouse   194 EYECSAENDVSFPDVKKVRVIVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKRL 258

  Fly   283 -EGQ--------STIGSLIIESAKKRDTGNYTCSPSN---SPSATVTLNIINGESSASAVTSSAA 335
             .||        ||...|.:.:..:...|||||..:|   :.:|::.||.|...:::|.|||.|.
Mouse   259 FNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNQIIEPTTSSPVTSPAP 323

  Fly   336 TTRAYALS----------ILALLLSVIL 353
            :|..|.::          .|||.||.::
Mouse   324 STAQYGITGSACDLFSCWSLALTLSSVI 351

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr11NP_001262320.1 I-set 125..216 CDD:254352 26/97 (27%)
Ig 127..217 CDD:299845 25/96 (26%)
IG_like 227..320 CDD:214653 33/169 (20%)
IGc2 234..311 CDD:197706 30/153 (20%)
Negr1XP_036019026.1 FR1 38..55 CDD:409353 5/16 (31%)
Ig strand A' 40..46 CDD:409353 1/5 (20%)
IG_like 41..129 CDD:214653 26/96 (27%)
Ig strand B 48..56 CDD:409353 3/7 (43%)
CDR1 56..60 CDD:409353 0/3 (0%)
FR2 61..68 CDD:409353 2/7 (29%)
Ig strand C 61..67 CDD:409353 2/6 (33%)
CDR2 69..79 CDD:409353 1/9 (11%)
Ig strand C' 71..74 CDD:409353 0/2 (0%)
Ig strand C' 76..79 CDD:409353 1/2 (50%)
FR3 80..115 CDD:409353 13/41 (32%)
Ig strand D 84..91 CDD:409353 2/11 (18%)
Ig strand E 94..100 CDD:409353 3/7 (43%)
Ig strand F 107..115 CDD:409353 3/7 (43%)
CDR3 116..120 CDD:409353 1/3 (33%)
Ig strand G 120..129 CDD:409353 3/9 (33%)
FR4 122..129 CDD:409353 2/6 (33%)
Ig strand A' 139..144 CDD:409353 1/4 (25%)
IGc2 146..204 CDD:197706 13/59 (22%)
Ig strand B 150..157 CDD:409353 3/6 (50%)
Ig strand C 163..168 CDD:409353 2/4 (50%)
Ig strand C' 170..172 CDD:409353 0/1 (0%)
Ig strand E 180..186 CDD:409353 0/5 (0%)
Ig strand F 193..200 CDD:409353 1/6 (17%)
Ig_3 219..295 CDD:404760 14/75 (19%)
putative Ig strand A 219..225 CDD:409353 1/5 (20%)
Ig strand B 235..239 CDD:409353 1/3 (33%)
Ig strand C 248..252 CDD:409353 0/3 (0%)
Ig strand E 274..278 CDD:409353 1/3 (33%)
Ig strand F 288..293 CDD:409353 4/4 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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