DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr11 and Fas2

DIOPT Version :9

Sequence 1:	NP_001262320.1	Gene:	dpr11 / 40800	FlyBaseID:	FBgn0053202	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_001284854.1	Gene:	Fas2 / 31364	FlyBaseID:	FBgn0000635	Length:	885	Species:	Drosophila melanogaster

Alignment Length:	363	Identity:	85/363 - (23%)
Similarity:	125/363 - (34%)	Gaps:	100/363 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 WK-NRSRSEMQTLETRVRPLQGAQLTQLLLGGILCLTIASHTQTSAEAAGGRVSGPGAGTSEGAG 67
            || ||:.:.:.....|.:|   ...|:.|.|..|.|.|   |..|.| .||:.
  Fly    69 WKDNRNNTILPKPNGRNQP---PMYTETLPGESLALMI---TSLSVE-MGGKY------------ 114

  Fly    68 TSSASAASTAISSDESGDPSSATAFSSLAQVSSLLPEASALSATSGLVEPYLDGYATSNVTTQIG 132
            ..:||.|:|.|.  |.|    .|..:.:|...:..||               :.|.|      :|
  Fly   115 YCTASYANTEIL--EKG----VTIKTYVAITWTNAPE---------------NQYPT------LG 152

  Fly   133 THAYLPCRVKQLGNKSVSWIRLRDGHILTVDRAVFIADQRFLAIKQPDKYWTLQIKYVQARDAGS 197
            ....:.|.||...|.::.|:|..|....|.|:.|...:             .|.|:.||..|.|.
  Fly   153 QDYVVMCEVKADPNPTIDWLRNGDPIRTTNDKYVVQTN-------------GLLIRNVQESDEGI 204

  Fly   198 YECQ---VSTEPKVSARVQLQVVVPRTEILGEPDRY-VKAGSNVVLRCIVRGALEPPTFIMWYHG 258
            |.|:   :.|...:...::::|.: :.||:..|... ...|......|..||  :|...|.|...
  Fly   205 YTCRAAVIETGELLERTIRVEVFI-QPEIISLPTNLEAVEGKPFAANCTARG--KPVPEISWIRD 266

  Fly   259 AEQL---AADSRRHRTQLDPNLPEASGEGQSTIGSLIIESAKKRDTGNYTCSPSN---------- 310
            |.||   .||    |.|::|.           .|.:.|.|..:.|.|.|||...|
  Fly   267 ATQLNVATAD----RFQVNPQ-----------TGLVTISSVSQDDYGTYTCLAKNRAGVVDQKTK 316

  Fly   311 -----SPSATVTLNIINGESSASAVTSSAATTRAYALS 343
                 .|......|:....:...|:|..|....|.|::
  Fly   317 LNVLVRPQIYELYNVTGARTKEIAITCRAKGRPAPAIT 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr11	NP_001262320.1	I-set	125..216	CDD:254352	20/93 (22%)
		Ig	127..217	CDD:299845	20/92 (22%)
		IG_like	227..320	CDD:214653	26/111 (23%)
		IGc2	234..311	CDD:197706	24/94 (26%)
Fas2	NP_001284854.1	IG_like	39..133	CDD:214653	25/88 (28%)
		IG_like	144..226	CDD:214653	24/115 (21%)
		IGc2	152..209	CDD:197706	19/69 (28%)
		I-set	230..319	CDD:254352	27/105 (26%)
		IGc2	243..309	CDD:197706	24/82 (29%)
		IG_like	330..424	CDD:214653	6/25 (24%)
		IGc2	339..412	CDD:197706	5/16 (31%)
		Ig	447..518	CDD:143165
		fn3	534..611	CDD:278470
		FN3	640..735	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810